PMID: 9162520Apr 1, 1996Paper

Why do so many cancer patients fail to respond to interferon therapy?

Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research
S Einhorn, D Grander

Abstract

Since their first use in the clinic some 25 years ago, interferons (IFNs) have become accepted therapy in a range of cancer forms. However, although in some patients they induce remission, in the great majority they are of no benefit or, at best, lead only to minor improvements. This review considers possible reasons for these failures.

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