Why do some depressed outpatients who are in remission according to the Hamilton Depression Rating Scale not consider themselves to be in remission?

The Journal of Clinical Psychiatry
Mark ZimmermanMoataz Rahgeb

Abstract

In treatment studies of depression, remission is typically defined narrowly, based on scores on symptom severity scales. Patients treated in clinical practice, however, define the concept of remission more broadly and consider functional status, coping ability, and life satisfaction as important indicators of remission status. In the present report from the Rhode Island Methods to Improve Diagnostic Assessment and Services project, we examined how many depressed patients in ongoing treatment who scored in the remission range on the 17-item Hamilton Depression Rating scale (HDRS) did not consider themselves to be in remission from their depression. Among the HDRS remitters, we compared the demographic and clinical characteristics of patients who did and did not consider themselves to be in remission. From March 2009 to July 2010, we interviewed 274 psychiatric outpatients diagnosed with DSM-IV major depressive disorder who were in ongoing treatment. The patients completed measures of depressive and anxious symptoms, psychosocial functioning, and quality of life. Approximately one-half of the patients scoring 7 and below on the HDRS (77 of 140 patients for whom self-reported remission status was available) did not consider themse...Continue Reading

Citations

Aug 21, 2014·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·David A FishbainJinrun Gao
Oct 30, 2012·Journal of Psychiatric Research·Mark ZimmermanMoataz Ragheb
Oct 12, 2013·Depression and Anxiety·Mark ZimmermanDaniela A Boerescu
Mar 14, 2013·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Heinz GrunzeUNKNOWN WFSBP Task Force on Treatment Guidelines for Bipolar Disorders
Dec 30, 2014·Journal of Affective Disorders·Koen DemyttenaereKees van Heeringen
Oct 25, 2016·Journal of Affective Disorders·Manish K JhaMadhukar H Trivedi
Dec 21, 2016·Cognitive Neuropsychiatry·Christopher R BowieSarah Cassidy
Jun 10, 2017·International Clinical Psychopharmacology·Koichiro WatanabeSusan Kornstein
Jun 6, 2015·Asia-Pacific Psychiatry : Official Journal of the Pacific Rim College of Psychiatrists·Diego NovickJosep Maria Haro
Aug 23, 2019·Neurology and Therapy·Maggie McCueClément François
Feb 6, 2020·Psychotherapy Research : Journal of the Society for Psychotherapy Research·Melissa Miléna De SmetMattias Desmet
Oct 13, 2017·The International Journal of Neuropsychopharmacology·Oloruntoba J OlubokaPierre Blier
Apr 12, 2019·Frontiers in Psychology·Melissa Miléna De SmetMattias Desmet
Dec 21, 2019·JAMA : the Journal of the American Medical Association·Klaus MunkholmAsger Sand Paludan-Müller
May 26, 2017·European Psychiatry : the Journal of the Association of European Psychiatrists·B KarpovE Isometsä
Feb 5, 2021·Psychotherapy Research : Journal of the Society for Psychotherapy Research·Mattias DesmetGünter Schiepek
Jun 20, 2021·Acta Psychiatrica Scandinavica·Fredrik HieronymusSøren Dinesen Østergaard

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.