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Widespread correlation of KRAB zinc finger protein binding with brain-developmental gene expression patterns

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences

Feb 23, 2020

Grace FarmiloeFrank M J Jacobs

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PubMed

Abstract

The large family of KRAB zinc finger (KZNF) genes are transcription factors implicated in recognizing and repressing repetitive sequences such as transposable elements (TEs) in our genome. Through successive waves of retrotransposition-mediated insertions, various classes of TEs have in...read more

Mentioned in this Paper

Protein Binding
Tf2-6 protein, S pombe
Operator gene
Problem
Transcription Factor
Brain Development
DNA Transposable Elements
Biological Evolution
Retrotransposition
ZKSCAN1 gene
7
Paper Details
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Widespread correlation of KRAB zinc finger protein binding with brain-developmental gene expression patterns

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences

Feb 23, 2020

Grace FarmiloeFrank M J Jacobs

PMID: 32075554

DOI: 10.1098/rstb.2019.0333

Abstract

The large family of KRAB zinc finger (KZNF) genes are transcription factors implicated in recognizing and repressing repetitive sequences such as transposable elements (TEs) in our genome. Through successive waves of retrotransposition-mediated insertions, various classes of TEs have in...read more

Mentioned in this Paper

Protein Binding
Tf2-6 protein, S pombe
Operator gene
Problem
Transcription Factor
Brain Development
DNA Transposable Elements
Biological Evolution
Retrotransposition
ZKSCAN1 gene
7

Feeds With Similar Papers

Transposable Elements

Transposable elements (tes) have profound effects on the structure, function and evolution of their host genomes.

Genetic Influences on Brain Development

The genetic landscape of an individual can have drastic effects on brain development and brain developmental disorders. Discover the latest research here.

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