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Widespread signals of convergent adaptation to high altitude in Asia and america

American Journal of Human Genetics

Sep 30, 2014

Matthieu FollLaurent Excoffier

Abstract

Living at high altitude is one of the most difficult challenges that humans had to cope with during their evolution. Whereas several genomic studies have revealed some of the genetic bases of adaptations in Tibetan, Andean, and Ethiopian populations, relatively little evidence of conver...read more

Mentioned in this Paper

Genetic Drift
Genome-Wide Association Study
In Silico
Interferon Gamma Measurement
Biochemical Pathway
EGLN1
Phosphatidylinositols
SERPINA1 gene
Meta-Analysis (Publications)
DNA Copy Number Changes
33
151
Paper Details
References
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  • Citations29
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  • References53
  • Citations29
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Widespread signals of convergent adaptation to high altitude in Asia and america

American Journal of Human Genetics

Sep 30, 2014

Matthieu FollLaurent Excoffier

PMID: 25262650

DOI: 10.1016/j.ajhg.2014.09.002

Abstract

Living at high altitude is one of the most difficult challenges that humans had to cope with during their evolution. Whereas several genomic studies have revealed some of the genetic bases of adaptations in Tibetan, Andean, and Ethiopian populations, relatively little evidence of conver...read more

Mentioned in this Paper

Genetic Drift
Genome-Wide Association Study
In Silico
Interferon Gamma Measurement
Biochemical Pathway
EGLN1
Phosphatidylinositols
SERPINA1 gene
Meta-Analysis (Publications)
DNA Copy Number Changes
33
151

Similar Papers Found In These Feeds

Genome Dynamics and Adaptation

Genome-scale tools are revolutionizing studies of evolution by providing complete determination of the genetic basis of adaptation. Discover the latest research on Genome Dynamics and Adaptation here.

Immune Therapies In Cancer

Immunotherapy in cancer is used to help the immune system fight against invading cancer cells. It is used to slow the progression of the disease and prevent metastasis while enhancing the immune response. There are different types, including monoclonal antibodies and checkpoint inhibitors. Here is the latest research on immune therapies in cancer.

Related Papers

Paper Details
References
  • References53
  • Citations29
12345...
  • References53
  • Citations29
123
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