Will genetically modified foods be allergenic?

The Journal of Allergy and Clinical Immunology
S L Taylor, Susan L Hefle

Abstract

Foods produced through agricultural biotechnology, including such staples as corn, soybeans, canola, and potatoes, are already reaching the consumer marketplace. Agricultural biotechnology offers the promise to produce crops with improved agronomic characteristics (eg, insect resistance, herbicide tolerance, disease resistance, and climatic tolerance) and enhanced consumer benefits (eg, better taste and texture, longer shelf life, and more nutritious). Certainly, the products of agricultural biotechnology should be subjected to a careful and complete safety assessment before commercialization. Because the genetic modification ultimately results in the introduction of new proteins into the food plant, the safety, including the potential allergenicity, of the newly introduced proteins must be assessed. Although most allergens are proteins, only a few of the many proteins found in foods are allergenic under the typical circumstances of exposure. The potential allergenicity of the introduced proteins can be evaluated by focusing on the source of the gene, the sequence homology of the newly introduced protein to known allergens, the expression level of the novel protein in the modified crop, the functional classification of the nove...Continue Reading

References

May 1, 1991·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S H ArshadD W Hide
Jul 1, 1990·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A HøstO Osterballe
Nov 1, 1989·The Journal of Allergy and Clinical Immunology·J Bernhisel-BroadbentH A Sampson
Dec 1, 1988·The Journal of Allergy and Clinical Immunology·S A BockD D Metcalfe
Feb 1, 1986·The Journal of Allergy and Clinical Immunology·S Machtinger, R Moss
Apr 1, 1983·Archives of Disease in Childhood·P P van AsperenC M Mellis
Mar 1, 1980·Clinical Allergy·J O Warner
Apr 1, 1994·The Journal of Allergy and Clinical Immunology·R SorvaK Juntunen-Backman
Mar 14, 1996·The New England Journal of Medicine·J A NordleeR K Bush
Jan 1, 1996·Critical Reviews in Food Science and Nutrition·A Trius, J G Sebranek
Jan 1, 1996·Critical Reviews in Food Science and Nutrition·S L HefleS L Taylor
Jan 1, 1996·Critical Reviews in Food Science and Nutrition·S L Taylor, S B Lehrer
Jan 1, 1996·Critical Reviews in Food Science and Nutrition·D D MetcalfeR L Fuchs
Jun 1, 1997·The Journal of Allergy and Clinical Immunology·H S NelsonD Leung
Oct 6, 1997·The Journal of Allergy and Clinical Immunology·M J van der VeenJ S van der Zee
May 30, 1998·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·L M KnippelsG F Houben
Oct 1, 1996·Nature Biotechnology·J D AstwoodR L Fuchs
Sep 8, 1998·Microbiology and Molecular Biology Reviews : MMBR·E SchnepfD H Dean
Oct 3, 1999·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·L M KnippelsG F Houben
Jul 11, 2000·The Journal of Allergy and Clinical Immunology·H Breiteneder, C Ebner
Nov 9, 2000·Regulatory Toxicology and Pharmacology : RTP·F S BetzR L Fuchs
Feb 15, 2003·FEMS Microbiology Reviews·Manuel Porcar, Victor Juárez-Pérez
Nov 22, 2007·Journal of Pediatric Gastroenterology and Nutrition·Bodo Niggemann, Kirsten Beyer
Nov 1, 1997·Environmental Toxicology and Pharmacology·R C Aalberse
Nov 1, 1997·Environmental Toxicology and Pharmacology·S L Taylor
Nov 1, 1997·Environmental Toxicology and Pharmacology·G F HoubenA H Penninks

❮ Previous
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Citations

Nov 30, 2005·The Proceedings of the Nutrition Society·Rebecca J Dearman, Ian Kimber
Jan 25, 2002·Annual Review of Pharmacology and Toxicology·Steve L Taylor
Jun 11, 2005·International Archives of Allergy and Immunology·Richard E GoodmanRonald van Ree
Jun 11, 2005·International Archives of Allergy and Immunology·Armin SpökRudolf Valenta
Jul 5, 2003·Biological & Pharmaceutical Bulletin·Kayoko TakagiJun-ichi Sawada
Feb 8, 2003·Environmental Health Perspectives·Ian KimberRebecca J Dearman
Feb 8, 2003·Environmental Health Perspectives·Marcia SticklerFiona Harding
Mar 5, 2008·Bioinformation·Kandaswamy Krishna Kumar, Prakash Shrikrishna Shelokar
Nov 18, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·R J DearmanI Kimber
Nov 18, 2003·Allergy·V BrusicS J Stelman
Nov 1, 2012·Journal of Immunotoxicology·Na SunHuilian Che
Jan 22, 2015·Critical Reviews in Food Science and Nutrition·Katrine Lindholm Bøgh, Charlotte Bernhard Madsen
Mar 5, 2016·Food & Nutrition Research·Amjad IqbalIn-Jung Lee
Dec 13, 2006·Methods : a Companion to Methods in Enzymology·Rebecca J Dearman, Ian Kimber
Jun 5, 2002·Current Opinion in Allergy and Clinical Immunology·Steve L Taylor, Susan L Hefle
Mar 16, 2002·Current Allergy and Asthma Reports·Ricki M Helm
Nov 1, 2005·Expert Review of Clinical Immunology·Richard E Goodman, Sue L Hefle
Aug 20, 2009·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K L BøghC B Madsen
Apr 24, 2003·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Michael B Stadler, Beda M Stadler
Oct 24, 2002·Journal of Pediatric Gastroenterology and Nutrition·Hilary A Perr
Jan 27, 2005·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Eva UntersmayrErika Jensen-Jarolim
May 23, 2002·Annals of the New York Academy of Sciences·Tong-Jen Fu
Aug 7, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Vanessa SmartS P Hogan
Sep 9, 2005·World Journal of Gastroenterology : WJG·Xu-Dong JiaXiao-Guang Yang
Jan 1, 2011·Clinical and Translational Allergy·Apostolos BossiosPhotini Papageorgiou
May 15, 2003·Plant Physiology·Eliot M HermanAnthony J Kinney
Oct 9, 2001·The Journal of Allergy and Clinical Immunology·J A BernsteinD I Bernstein
Mar 8, 2011·The Journal of Allergy and Clinical Immunology·Gustavo MartosAnna Nowak-Węgrzyn
Dec 26, 2006·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·F Javier Moreno
Mar 1, 2012·Journal of Agricultural and Food Chemistry·Katrine L BøghCharlotte B Madsen
Jun 10, 2008·The Journal of Allergy and Clinical Immunology·Eva Untersmayr, Erika Jensen-Jarolim

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