Willingness of Chinese injection drug users to participate in HIV vaccine trials

Vaccine
Lu YinYiming Shao

Abstract

Chinese injection drug users (IDUs) may be a proper candidate population for HIV vaccine trials. To evaluate willingness to participate (WTP) in HIV vaccine trials among Chinese IDUs. Questionnaire interviews were completed among 401 IDUs in Urumqi City in northwestern China in 2005. Overall 74.3% of participants said that they would be definitely willing to participate in HIV vaccine trials, 17.7% were probably willing, 6.2% were probably not willing, and remaining 1.8% were definitely not willing to join. Multivariate logistic regression analysis demonstrated that WTP was positively associated with having ever had sex with a drug use partner (adjusted odds ratio [AOR]: 1.8; 95% confidence interval [CI]: 1.04, 3.2), sharing needle and syringe with a new drug use partner in the past 3 months (AOR: 3.8; 95% CI: 1.2, 11.7), perceived family support for participation (AOR: 7.4; 95% CI: 4.3, 12.7), and perceived vaccine protection against HIV infection (AOR: 16.1; 95% CI: 3.7, 70.8), and was negatively associated with perceived risk of social stigma and isolation for participation (AOR: 0.3; 95% CI: 0.2, 0.5). The stated WTP in hypothetical HIV vaccine trials was high among Chinese IDUs. Further studies are needed to evaluate actua...Continue Reading

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Citations

Feb 6, 2010·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Lingjie LiaoYiming Shao
Feb 7, 2009·Expert Review of Vaccines·Chuen-Yen LauZuhayr Kafaar
Feb 12, 2009·Tropical Medicine & International Health : TM & IH·Eugene RuzagiraAnatoli Kamali
Oct 31, 2015·Psychology, Health & Medicine·Shayesta Dhalla
Jun 24, 2010·Journal of Empirical Research on Human Research Ethics : JERHRE·Celia B Fisher
Dec 20, 2018·Tropical Medicine & International Health : TM & IH·Joyce L BrowneRieke van der Graaf

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