PMID: 15224559Jul 1, 2004Paper

Wilson's disease: study of 6 neurologic forms observed at the University Hospital in Conakry

Médecine tropicale : revue du Corps de santé colonial
A CisséL Da Silva

Abstract

This report describes 6 cases of Wilson's disease observed at the University Hospital Center in Conakry, Guinea. Presenting symptoms involved extrapyramidal syndrome in 4 cases, psychomotor epilepsy in 1, and confusional syndrome in 1 case. Diagnosis was based on neuropsychic manifestations, Kayser-Fleicher corneal ring, liver failure, and impaired copper metabolism. Brain CT-scan depicted normal features in 3 cases, symmetric hypodensity of the lenticular nucleus in one, discrete ventricular dilatation of in one a and cortico-subcoetical atrophy in one.

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