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Winning the Tug-of-War Between Effector Gene Design and Pathogen Evolution in Vector Population Replacement Strategies

Frontiers in Genetics

Oct 30, 2019

John M. MarshallOmar S. Akbari

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Abstract

While efforts to control malaria with available tools have stagnated, and arbovirus outbreaks persist around the globe, the advent of clustered regularly interspaced short palindromic repeat (CRISPR)-based gene editing has provided exciting new opportunities for genetics-based strategie...read more

Mentioned in this Paper

Antimalarials
Antiviral Agents
Arboviruses
Chikungunya virus
Clinical Trials
Dengue Fever
Disease Susceptibility
Biological Evolution
Genes
Genetic Vectors
11
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Winning the Tug-of-War Between Effector Gene Design and Pathogen Evolution in Vector Population Replacement Strategies

Frontiers in Genetics

Oct 30, 2019

John M. MarshallOmar S. Akbari

PMID: 31737050

DOI: 10.3389/fgene.2019.01072

Abstract

While efforts to control malaria with available tools have stagnated, and arbovirus outbreaks persist around the globe, the advent of clustered regularly interspaced short palindromic repeat (CRISPR)-based gene editing has provided exciting new opportunities for genetics-based strategie...read more

Mentioned in this Paper

Antimalarials
Antiviral Agents
Arboviruses
Chikungunya virus
Clinical Trials
11

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