Wire mesh allows more revascularization than a strut in impaction bone grafting: an animal study in goats

Clinical Orthopaedics and Related Research
Stefan B T BolderPieter Buma

Abstract

Segmental defects can be reconstructed with a cortical strut or a metal wire mesh when using bone impaction grafting in the femur. We hypothesized that structural grafts would negatively influence revascularization of the underlying impacted grafts compared with an open wire mesh. A standardized large medial wall defect was reconstructed with a strut or a mesh in six goats per group. In all femurs impaction grafting was done in combination with a cemented collarless double-tapered highly polished Exeter stem. After 6 weeks the femurs were harvested. A high rate of periprosthetic fractures was observed (three of seven and two of six for the strut and mesh groups, respectively). Histologic analysis showed different revascularization and tissue ingrowth patterns for both reconstruction techniques. In the strut group, fibrous tissue ingrowth was limited to the edges of the defect. Medially behind the strut no or limited fibrous tissue ingrowth was found. In the mesh group, fibrous tissue and blood vessels penetrated the mesh and a superficial zone of revascularized grafts was observed. Although revascularization, concomitant graft resorption and bone incorporation may compromise the short-term stability of the stem after surgery, t...Continue Reading

References

Dec 1, 1984·Acta Orthopaedica Scandinavica·T J SlooffA J Lemmens
Sep 1, 1993·The Journal of Bone and Joint Surgery. British Volume·R S LingL Linder
Jan 1, 1993·The Journal of Bone and Joint Surgery. British Volume·G A GieA J Timperley
Aug 1, 1997·The Journal of Arthroplasty·J D EldridgeI D Learmonth
Apr 1, 1998·Archives of Orthopaedic and Trauma Surgery·G Ullmark, L Linder
Apr 29, 1998·The Orthopedic Clinics of North America·C P DuncanB A Masri
Feb 29, 2000·Clinical Orthopaedics and Related Research·W C Head, T I Malinin
May 1, 2001·Acta Orthopaedica Scandinavica·M Tägil, P Aspenberg
May 25, 2001·Acta Orthopaedica Scandinavica·P Aspenberg
Jan 31, 2002·Acta Orthopaedica Scandinavica·B W Schreurs, P Buma
Feb 23, 2002·Clinical Orthopaedics and Related Research·Sanne van der DonkB Willem Schreurs

❮ Previous
Next ❯

Citations

Feb 8, 2008·The Journal of Bone and Joint Surgery. British Volume·M ButtaroF Piccaluga
Apr 5, 2014·Operative Orthopädie und Traumatologie·I C HeyligersE H van Haaren
Apr 21, 2007·International Orthopaedics·Agustín José GualaFrancisco Piccaluga
Aug 16, 2008·Clinical Orthopaedics and Related Research·Martín A ButtaroFrancisco Piccaluga
Oct 31, 2009·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Martin A ButtaroFrancisco Piccaluga
Mar 17, 2010·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Jessica J AlmHannu T Aro
Mar 19, 2009·Clinical Orthopaedics and Related Research·Martín A ButtaroFrancisco Piccaluga
Jan 15, 2009·Clinical Orthopaedics and Related Research·Pieter H J BullensPieter Buma
Sep 5, 2006·The Journal of Bone and Joint Surgery. American Volume·B Willem SchreursJean W M Gardeniers

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.