WNT Signaling in Disease

Cells
Li Fang NgNicholas S Tolwinski

Abstract

Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide range of pathologies in humans. Here, we discuss the WNT pathway and its role in human disease and some of the advances in WNT-related treatments.

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Methods Mentioned

BETA
GTPases
ubiquitination
xenograft
xenografts

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