Wnt signaling targets ETO coactivation domain of TAF4/TFIID in vivo.

Proceedings of the National Academy of Sciences of the United States of America
Kevin J Wright, Robert Tjian

Abstract

Understanding the diverse activities of the multisubunit core promoter recognition complex TFIID in vivo requires knowledge of how individual subunits contribute to overall functions of this TATA box-binding protein (TBP)/TBP-associated factor (TAF) complex. By generating altered holo-TFIID complexes in Drosophila we identify the ETO domain of TAF4 as a coactivator domain likely targeted by Pygopus, a protein that is required for Wingless-induced transcription of naked cuticle. These results establish a coactivator function of TAF4 and provide a strategy to dissect mechanisms of TFIID function in vivo.

References

Nov 26, 1996·Proceedings of the National Academy of Sciences of the United States of America·N TaneseA Admon
Apr 7, 2000·The Journal of Biological Chemistry·J C ReeseH Kurpad
Jun 8, 2002·The Journal of Biological Chemistry·Mohammed FilaliJohn F Engelhardt
Mar 28, 2006·The Journal of Biological Chemistry·Seokjoong KimThomas G Boyer
May 23, 2006·Current Biology : CB·Reto StädeliKonrad Basler
Jun 6, 2006·Genes & Development·Michael T MarrRobert Tjian
Aug 10, 2006·Proceedings of the National Academy of Sciences of the United States of America·Kevin J WrightRobert Tjian
Sep 27, 2006·Molecular and Cellular Biology·Haiying ZhouThomas G Boyer
Feb 27, 2007·Current Biology : CB·Marc de la Roche, Mariann Bienz
May 8, 2007·Proceedings of the National Academy of Sciences of the United States of America·Xiaoping WangRaymond H Jacobson
Nov 13, 2007·Nature Genetics·Ginger W MuseKaren Adelman
May 3, 2008·Proceedings of the National Academy of Sciences of the United States of America·Inés CarreraJessica E Treisman

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Citations

Mar 3, 2009·Proceedings of the National Academy of Sciences of the United States of America·Tanushri SenguptaJames J Bieker
Jan 29, 2009·Proceedings of the National Academy of Sciences of the United States of America·Michael T Marr
Mar 4, 2011·Proceedings of the National Academy of Sciences of the United States of America·Joseph A D'AlessioRobert Tjian
Jan 13, 2010·Cold Spring Harbor Perspectives in Biology·Ken M Cadigan, Mark Peifer
Jul 23, 2013·Genes & Development·Wei-Yi ChenRobert G Roeder
May 5, 2010·Genes & Development·Haiyun SongKonrad Basler
Sep 23, 2014·International Journal of Molecular Sciences·Jekaterina Kazantseva, Kaia Palm
Jul 6, 2010·Current Opinion in Genetics & Development·Ferenc MüllerLàszlò Tora
Jun 6, 2009·Mechanisms of Development·Roman KesslerKonrad Basler
Mar 31, 2015·Nature Immunology·Matthew S MillerIvan Marazzi
Jul 18, 2020·Biochemical Society Transactions·Yan ShiPing Zhu
Jul 13, 2014·Journal of Cell Science·Gengqiang XieWu-Min Deng

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