Wnt signaling: the many interfaces of β-catenin

Current Biology : CB
Mira I Pronobis, Mark Peifer

Abstract

Wnt signaling regulates virtually every cell fate decision during development. How can the same signal trigger such diverse events? Engaging different transcriptional machinery via different protein interfaces on the transcriptional co-activator β-catenin provides part of the answer.

References

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Jan 13, 2010·Cold Spring Harbor Perspectives in Biology·Ken M Cadigan, Mark Peifer
Dec 23, 2011·Genes & Development·Tomas ValentaKonrad Basler

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