Wolbachia strain wAu efficiently blocks arbovirus transmission in Aedes albopictus.

PLoS Neglected Tropical Diseases
M. V. ManciniSteven P Sinkins

Abstract

The global incidence of arboviral diseases transmitted by Aedes mosquitoes, including dengue, chikungunya, yellow fever, and Zika, has increased dramatically in recent decades. The release of Aedes aegypti carrying the maternally inherited symbiont Wolbachia as an intervention to control arboviruses is being trialled in several countries. However, these efforts are compromised in many endemic regions due to the co-localization of the secondary vector Aedes albopictus, the Asian tiger mosquito. Ae. albopictus has an expanding global distribution following incursions into a number of new territories. To date, only the wMel and wPip strains of Wolbachia have been reported to be transferred into and characterized in this vector. A Wolbachia strain naturally infecting Drosophila simulans, wAu, was selected for transfer into a Malaysian Ae. albopictus line to create a novel triple-strain infection. The newly generated line showed self-compatibility, moderate fitness cost and complete resistance to Zika and dengue infections.

References

Sep 22, 1995·Proceedings. Biological Sciences·S P SinkinsS L O'Neill
May 3, 2003·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·María G Guzman, Gustavo Kouri
May 24, 2003·Memórias do Instituto Oswaldo Cruz·Nildimar Alves HonórioRicardo Lourenço-de-Oliveira
Dec 26, 2006·Vector Borne and Zoonotic Diseases·Konstantin TsetsarkinDana L Vanlandingham
Apr 10, 2007·Vector Borne and Zoonotic Diseases·Mark Q BenedictL Philip Lounibos
Apr 29, 2008·Emerging Infectious Diseases·Paolo BonilauriMichele Dottori
Sep 17, 2008·Nature Reviews. Microbiology·John H WerrenMichael E Clark
Nov 1, 2008·Science·Lauren M HedgesKaryn N Johnson
Oct 13, 2009·Applied and Environmental Microbiology·Eunho SuhStephen L Dobson
Jun 23, 2011·PLoS Neglected Tropical Diseases·Man-Koumba SoumahoroThomas Hanslik
Nov 30, 2011·Proceedings of the National Academy of Sciences of the United States of America·Marcus S C BlagroveSteven P Sinkins
Jul 31, 2012·Applied and Environmental Microbiology·Sheree E OsborneKaryn N Johnson
Aug 1, 2012·PLoS Neglected Tropical Diseases·Peng LuZhiyong Xi
Apr 5, 2013·PLoS Neglected Tropical Diseases·Marcus S C BlagroveSteven P Sinkins
Aug 7, 2013·Trends in Parasitology·Mariangela BonizzoniAnthony A James
Sep 27, 2013·PLoS Pathogens·Peter KriesnerAndrew R Weeks
Sep 4, 2014·Asian Pacific Journal of Tropical Biomedicine·Sylvia JoanneJonathan Inbaraj Doss
Oct 25, 2014·BMC Genomics·Elizabeth R SuttonSteven P Sinkins
Sep 15, 2015·Evolutionary Applications·Ary A HoffmannGordana Rašić
Jul 28, 2016·PLoS Neglected Tropical Diseases·Jill N UlrichLeon E Hugo
Mar 2, 2017·Nature Microbiology·John F BeckmannMark Hochstrasser
Apr 22, 2017·Emerging Infectious Diseases·Alexander T CiotaLaura D Kramer
May 17, 2018·Evolution; International Journal of Organic Evolution·Peter Kriesner, Ary A Hoffmann
Mar 6, 2019·Nature Microbiology·Moritz U G KraemerNick Golding
Apr 3, 2019·Journal of Trauma & Dissociation : the Official Journal of the International Society for the Study of Dissociation (ISSD)·Giovanni B Caputo

❮ Previous
Next ❯

Citations

Feb 16, 2021·Frontiers in Microbiology·Francesca ScolariMariangela Bonizzoni
May 9, 2021·Parasites & Vectors·Ranju Ravindran Santhakumari ManojDomenico Otranto
Oct 28, 2021·The Journal of General Virology·Ayda Susana Ortiz-BaezEdward C Holmes

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR

Software Mentioned

R
R Studio

Related Concepts

© 2021 Meta ULC. All rights reserved