PMID: 2091427Dec 1, 1990Paper

Wolff's law of transformation after 100 years

Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca
J Hert

Abstract

In the introduction to the article the author briefly describes the history of the Wolff's invention that under the influence of the function the bone structure is restructuring. This functional adaptation however, has not been fully clarified until these days. At present the general scheme of the fundamental adaptation mechanism has been generally adopted according to which the bone responds to the inner strain by aposition of the new bone while inactivity results in resorption. The author's own experiment as well as modern experiments carried out by the Lanyon group have proved that the starting point for reaction is intermittent loading in which both pressure and tension have the same effect. The strain results in the deformation of the bone tissue which is by an unclear yet way perceived and signalled to the superficial osteoblasts. However, not all cases of the functional adaptation of the bone can be explained in this way, first of all the remodelling of deformities after fractures or the modelling of metaphysis and the lateral drift of diaphysis in the course of normal growth. In comparison to Currey and other authors who therefore share the view that there does not exist a uniform algorithm of the functional adaptation ...Continue Reading

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