Women and lung cancer: does oestrogen play a role?

The Lancet Oncology
J M Siegfried

Abstract

Smoking-related disease remains a major public-health problem. Large numbers of women continue to smoke, and new smokers are almost as likely to be female as male. Lung cancer is still a largely incurable disease; annual lung-cancer mortality in women exceeds that of breast cancer, and lung cancer now accounts for 12% of all new female cancer cases. The results of several studies suggest that women are more susceptible than men to lung cancer and to conditions that predispose to this cancer, such as chronic obstructive pulmonary disease. There is still much controversy about whether there is an increased lung-cancer risk in women across all populations. Many epidemiological studies have been negative or equivocal when comparing male and female lung-cancer risk. This article is not intended to be a comprehensive review of all epidemiological studies, or of all possible lung-cancer risk factors. Lung-cancer incidence and risk in women are discussed, and evidence for possible mechanisms of increased female risk are presented, including the role of oestrogen in the development of lung cancer.

References

Jun 1, 1991·The American Review of Respiratory Disease·Y ChenJ A Dosman
Oct 15, 1990·Cancer Research·P T CagleM R Schwartz
Nov 1, 1989·The Annals of Thoracic Surgery·T MitsudomiK Sugimachi
Nov 15, 1989·International Journal of Cancer. Journal International Du Cancer·H O AdamiL Bergkvist
Nov 15, 1987·International Journal of Cancer. Journal International Du Cancer·Y T GaoJ F Fraumeni
May 15, 1987·Cancer·H H McDuffieJ A Dosman
Dec 1, 1971·The Journal of Pharmacy and Pharmacology·A H BeckettP Jenner
Jul 1, 1982·The Annals of Thoracic Surgery·M M KirshH Sloan
Jul 15, 1995·American Journal of Epidemiology·G C KabatE L Wynder
Apr 1, 1995·The Journal of Family Practice·J R DiFranza, R A Lew
Dec 21, 1994·Journal of the National Cancer Institute·M C AlavanjaJ D Boice
Mar 1, 1994·The European Respiratory Journal·X XuL Wang
Jun 1, 1994·Journal of the National Cancer Institute·E Taioli, E L Wynder
Apr 22, 1993·International Journal of Cancer. Journal International Du Cancer·K E OsannT Taylor
Jun 5, 1996·Journal of the National Cancer Institute·N Weiss
Jul 29, 1996·International Journal of Cancer. Journal International Du Cancer·U KaiserK Havemann
Jan 1, 1996·Annual Review of Public Health·V L Ernster
Jan 1, 1996·Annual Review of Pharmacology and Toxicology·J D Yager, J G Liehr
Sep 26, 1996·The New England Journal of Medicine·D R GoldD W Dockery
Mar 1, 1996·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·M L LiaoW Q You
Sep 15, 1996·American Journal of Epidemiology·A G SchwartzG M Swanson
Oct 23, 1997·Chest·E H Baldini, G M Strauss
Mar 14, 1998·Bioorganicheskaia khimiia·I B MertsalovV I Tsetlin
May 20, 1998·The International Journal of Eating Disorders·J L JarryC P Herman
Jan 12, 1999·American Journal of Epidemiology·S T MayneD T Janerich
Jan 29, 1999·Environmental Health Perspectives·D J SteckC F Lynch
Feb 2, 1999·Postgraduate Medical Journal·A H CrispC Stavrakaki
Dec 2, 1999·Journal of the National Cancer Institute·W P BennettC C Harris
Dec 2, 1999·Journal of the National Cancer Institute·H H NelsonK T Kelsey
Dec 22, 1999·International Journal of Epidemiology·S H JeeI S Kim
Dec 29, 1999·The Journal of Thoracic and Cardiovascular Surgery·M de PerrotA Spiliopoulos
Jan 6, 2000·Journal of the National Cancer Institute·S P ShriverJ M Siegfried
Feb 2, 2000·The Annals of Thoracic Surgery·M K FergusonE E Vokes
Apr 14, 2000·Clinics in Chest Medicine·L T Tanoue

❮ Previous
Next ❯

Citations

Jun 30, 2005·Cancer Causes & Control : CCC·Jill Everland LarsenKwun Meng Fong
Jul 2, 2009·Cancer Causes & Control : CCC·Lori MandelzweigSiegal Sadetzki
May 9, 2012·Cancer Causes & Control : CCC·Melissa C FriesenEllen A Eisen
May 27, 2004·Current Oncology Reports·Laura P Stabile, Jill M Siegfried
Jul 9, 2013·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Chun-hua XuLi-Ke Yu
Aug 21, 2003·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Petr ZatloukalLubos Petruzelka
Jul 17, 2008·Nature Clinical Practice. Oncology·Giannis MountziosJean-Charles Soria
Sep 21, 2007·Nature Reviews. Cancer·Sophie SunAdi F Gazdar
Jul 15, 2003·Respirology : Official Journal of the Asian Pacific Society of Respirology·Catherine Mee-ming WongChong-Kin Liam
Jan 26, 2012·The Journal of Biological Chemistry·Hsiang-Tsui WangMoon-shong Tang
Nov 18, 2005·Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews·Mihi Yang, Myung-Yun Pyo
Apr 26, 2003·International Journal of Epidemiology·Michaela KreuzerH-Erich Wichmann
May 18, 2006·Journal of the National Cancer Institute·Michael J ThunEugenia E Calle
Mar 7, 2002·Current Opinion in Oncology·Rafael RosellMiquel Taron
Jan 2, 2007·The Nurse Practitioner·Brooke M Simon
Oct 14, 2008·Journal of Occupational and Environmental Medicine·Sania AmrCurtis C Harris
Feb 15, 2011·Biochemistry. Biokhimii︠a︡·T A BogushM I Davydov
Aug 19, 2005·American Journal of Respiratory Cell and Molecular Biology·York E Miller
Jun 27, 2009·American Journal of Respiratory Cell and Molecular Biology·Margarita M IvanovaCarolyn M Klinge
Jan 14, 2012·Endocrine Reviews·Elizabeth A TownsendY S Prakash
Dec 25, 2008·Molecular Endocrinology·Guangfeng ZhangHarish Srinivas
Apr 24, 2012·Journal of Epidemiology·Meng-Hsuan ChengChun-Yuh Yang
Jan 25, 2011·AJR. American Journal of Roentgenology·Seth Kligerman, Charles White
Nov 11, 2011·The American Journal of Clinical Nutrition·Wan-Shui YangYong-Bing Xiang
Jun 24, 2010·Revue des maladies respiratoires·E QuoixUNKNOWN l'Intergroupe francophone de cancérologie thoracique (IFCT)
Nov 22, 2011·Revue des maladies respiratoires·E Quoix, E Lemarié
Sep 8, 2010·Cellular and Molecular Life Sciences : CMLS·Yvonne G J van HeldenJaap Keijer
Feb 27, 2009·Radiation and Environmental Biophysics·Kerstin BorgmannUlrike Hoeller
Feb 22, 2013·American Journal of Epidemiology·Anthony J AlbergMalcolm V Brock
Oct 14, 2008·American Journal of Epidemiology·Jocelyn M WeissWei Zheng
Apr 9, 2015·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Ann G SchwartzMichael S Simon
Sep 17, 2011·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Susana LinLih-Ann Li
Dec 19, 2015·Neoplasia : an International Journal for Oncology Research·Jill M SiegfriedLaura P Stabile
Dec 10, 2009·Seminars in Oncology·David PlanchardJean-Charles Soria
Jul 17, 2009·American Journal of Preventive Medicine·Lorraine J Greaves, Natalie J Hemsing
Dec 8, 2015·Journal of Preventive Medicine and Public Health = Yebang Ŭihakhoe Chi·Jong-Myon Bae, Eun Hee Kim
Oct 2, 2007·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Birgit Guldhammer SkovHelle Pappot
Jul 9, 2009·International Journal of Cancer. Journal International Du Cancer·Anita KoushikJack Siemiatycki
Oct 24, 2014·Cancer Science·Li-Han HsuShu-Huei Kao
Mar 24, 2005·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Eileen M ResnickSherry A Marts
Mar 22, 2005·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Norbert PaukEvzen Krepela

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved