Women-specific predictors of cardiovascular disease risk - new paradigms

International Journal of Cardiology
Silvia MaffeiWorking Group on "Gender difference in cardiovascular disease" of the Italian Society of Cardiology

Abstract

Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality in women in spite of the overall reduction in age-adjusted CVD mortality in the past few years. Although traditional risk factors for CVD are predictors of increased risk in both men and women, risk factors that are unique to women and related to their reproductive history have recently been considered to be important. The development of CVD in women may correlate with specific events taking place throughout a woman's obstetric and gynaecological history. Gynaecological conditions such as polycystic ovary syndrome, premature ovarian failure, surgical and spontaneous menopause, and conditions related to pregnancy, i.e. gestational diabetes, preeclampsia, intrauterine growth restriction, miscarriages, and preterm birth, may affect the onset, clinical features, and prognosis of CVD later in women's lives. These pathological conditions that develop during the fertile period of life or peri-menopause have been suggested to be early markers of future CVD; their presence presents a unique opportunity for the early identification of women who may be at an increased risk of CVD. The assessment of CV risk in women should not just focus on conventional risk fa...Continue Reading

Citations

Oct 18, 2020·Cardiovascular Drugs and Therapy·Pieter VynckierUNKNOWN EUROASPIRE V Investigators group
Aug 10, 2020·Menopause : the Journal of the North American Menopause Society·Jingyi WenShixuan Wang
Feb 23, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Cai-Rong ZhangGuang-Xia Ni
Feb 25, 2021·European Journal of Preventive Cardiology·Pieter VynckierUNKNOWN EUROASPIRE V Investigators group
Feb 23, 2021·Frontiers in Physiology·Mira Anette E HaukilahtiHeikki V Huikuri
Mar 20, 2021·Future Cardiology·Camilla CocchiAnna Vittoria Mattioli
Aug 28, 2021·American Journal of Perinatology·Max Jordan Nguemeni TiakoEugenia South

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