Wood dust exposure and the risk of upper aero-digestive and respiratory cancers in males

Occupational and Environmental Medicine
V JayaprakashM E Reid

Abstract

Wood dust (WD) has been designated a human carcinogen that can cause sino-nasal cancers. However, evidence of its association with other upper aero-digestive tract and respiratory (UADR) cancers is inconsistent. To examine the relationship between WD exposure and the risk of different histological subtypes of UADR cancers. In a hospital-based case-control study conducted at Roswell Park Cancer Institute, Buffalo, NY, USA, an examination was carried out to determine the effect of self-reported WD exposure on 1522 male UADR cancer cases (241 oral and oropharyngeal, 90 nasal cavity, nasopharyngeal and hypopharyngeal, 124 laryngeal, 809 lung and tracheal and 258 oesophagus and gastric cardia) and 1522 male controls, frequency matched on age and smoking history. Odds ratios (OR) were calculated after adjusting for relevant risk factors including tobacco smoking. The results show that regular WD exposure was associated with a statistically significant increased risk of 32% for all UADR cancers (OR 1.32; 95% CI 1.01 to 1.77; p-trend = 0.05) and 69% for lung cancer alone (OR 1.69; 95% CI 1.20 to 2.36; p-trend = 0.007). WD was associated with an 82-93% increased risk of squamous cell, small cell and adenocarcinoma of the lung and more t...Continue Reading

Citations

Nov 13, 2010·Occupational and Environmental Medicine·Parveen BhattiThomas L Vaughan
Jul 18, 2009·Archives of Medical Research·Xian-Lu ZhuoXue-Yuan Zhang
Jul 16, 2008·American Journal of Industrial Medicine·Heribert RamrothHeiko Becher
Dec 2, 2009·International Journal of Cancer. Journal International Du Cancer·Reetta HolmilaKirsti Husgafvel-Pursiainen
May 6, 2015·International Dental Journal·Bhawna GuptaNewell W Johnson
Jan 8, 2015·Environmental Health : a Global Access Science Source·Eric VallièresJack Siemiatycki
Feb 26, 2015·Mutagenesis·Sara StaffolaniLory Santarelli
Jul 25, 2015·International Journal of Environmental Research and Public Health·Annette C RohrAri Lewis
Dec 16, 2011·Journal of Biophotonics·Thomas Dreyer, Melanie Kreisel
Aug 26, 2011·Journal of Occupational and Environmental Medicine·Florence GuidaIsabelle Stücker
Jul 21, 2015·PloS One·Montserrat Alonso-SardónJosé Antonio Mirón-Canelo
Sep 21, 2019·Occupational and Environmental Medicine·Mireille MatratUNKNOWN ICARE Study Group
Dec 14, 2011·Journal of Occupational and Environmental Medicine·Sophie Paget-BaillyDanièle Luce
Aug 16, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Bhawna Gupta, Newell W Johnson
Mar 30, 2017·Annals of Work Exposures and Health·Jeroen DouwesJames D McGlothlin
May 27, 2020·Scientific Reports·Wanhyung LeeJin-Ha Yoon
Jun 8, 2018·Annals of Work Exposures and Health·Anne StraumforsWijnand Eduard

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Industrial Medicine
Carlos H BarcenasMargaret R Spitz
Cancer Detection and Prevention
John S NeubergerR William Field
The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases
Maria José Penna Maisonnette de Attayde SilvaAna Katherine da Silveira Gonçalves
© 2021 Meta ULC. All rights reserved