PMID: 18713510Aug 21, 2008Paper

Wood smoke-associated lung disease: a clinical, functional, radiological and pathological description

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
O Moran-MendozaF Vazquez-Alfaro

Abstract

Approximately half of the world's population, and up to 90% of households in rural areas of developing countries, depend on biomass for cooking and heating. The National Institute of Respiratory Diseases, México City. To describe wood smoke-associated lung disease (WSLD). Description of the clinical, functional and radiological manifestations of patients with WSLD, and a comparison of pathological findings of patients who died of WSLD and smokers who died of chronic bronchitis. All patients with WSLD were non-smoking women with chronic bronchitis, in whom asthma, bronchiectasis, tuberculosis, congestive heart failure, extreme obesity and alfa-1 antitrypsin deficiency had been excluded. All patients used wood for cooking and had been exposed to wood smoke for a median of 45 years. Dyspnoea, airway obstruction, air trapping, increased airway resistance, pathological evidence of anthracosis, chronic bronchitis, centrilobular emphysema and pulmonary hypertension were present in most patients with WSLD. Bronchial squamous metaplasia was a common finding. There were no significant differences in the histopathological findings between patients with WSLD and smokers. Diffuse interstitial fibrosis was absent in all patients. Patients wi...Continue Reading

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