Work-related sensitization and respiratory symptoms in carpentry apprentices exposed to wood dust and diisocyanates

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Paloma CampoMiguel Blanca

Abstract

Exposure to certain substances in the workplace may lead to sensitization and increased respiratory symptoms. To evaluate the frequency of work-related specific sensitization and respiratory symptoms in carpentry apprentices with occupational exposure to wood dust and diisocyanates. Apprentices (n=101) completed an occupational and symptoms questionnaire. Spirometry and skin prick tests to aeroallergens and to a battery of 14 different woods were performed in all the participants. Blood samples were collected for total IgE measurement and detection of specific IgE to diisocyanates. Half the participants (56%) had work-related respiratory symptoms: 54% due to wood dust, 15% due diisocyanates, and 9% to both. Participants with respiratory symptoms related to wood dust exposure had a significantly lower forced expiratory volume in 1 second compared with symptomatic individuals due to diisocyanates and asymptomatic individuals (P < .05). A history of rhinitis or asthma was associated with a 2.1- or 2.8-fold increase, respectively, in the likelihood of having respiratory symptoms due to wood dust exposure. Sensitization to wood was detected in 9% of participants, all of whom were atopic with a history of rhinitis and a high total Ig...Continue Reading

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Citations

Oct 8, 2011·Immunology and Allergy Clinics of North America·Santiago Quirce, Jonathan A Bernstein
Dec 8, 2015·Journal of Occupational and Environmental Medicine·Berran YucesoyDavid I Bernstein
Oct 21, 2015·Occupational Medicine·R E WiggansC M Barber
Apr 29, 2015·Toxicological Sciences : an Official Journal of the Society of Toxicology·Berran YucesoyDavid I Bernstein
Mar 4, 2011·Current Opinion in Allergy and Clinical Immunology·Santiago Quirce, Joaquín Sastre
Aug 26, 2014·Journal of Occupational and Environmental Medicine·Marcos RibeiroGary M Liss

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