Working Group report 4: exposure assessment for biological agents

American Journal of Industrial Medicine
Peter S ThorneBogumila Szponar

Abstract

This Working Group was assembled to review and evaluate methods currently used to estimate work site exposures to biological agents and to present recommendations on suitable measurement strategies. The current state of exposure assessment was evaluated for environments with organic dust including agriculture, composting, sewage and waste treatment processing, peat moss harvesting and handling, cotton and textile processing, greenhouse work, and grass seed processing. Methods for measurement of microbial contaminants in indoor environments were also considered. Important methods are emerging that use quantitative PCR for assessment of microbial agents. Difficulties exist with optimization of extraction to yield contaminant-free DNA without significant DNA loss. Advances in assays for microbial agents (e.g., endotoxin and glucans) as well as allergens have increased the utility of exposure assessment for these agents. A crucial area for further development is international harmonization of methodologies to reduce interlaboratory variability and to facilitate establishment of exposure guidelines. Endotoxin exposure assessment using the Limulus amebocyte lysate method is a high priority for harmonization because of its importance ...Continue Reading

References

Jan 1, 1994·Annual Review of Public Health·D W Dockery, C A Pope
Apr 1, 1994·Clinica Chimica Acta; International Journal of Clinical Chemistry·H TamuraT Kawai
Jan 1, 1994·American Journal of Industrial Medicine·P S Thorne
Feb 1, 1996·Journal of the Air & Waste Management Association·L Wallace
Oct 1, 1996·Journal of the Air & Waste Management Association·J SchwartzL M Neas
Jul 22, 1998·American Industrial Hygiene Association Journal·G J KullmanJ A Merchant
Aug 11, 1998·American Industrial Hygiene Association Journal·S RautialaP Kalliokoski
Mar 2, 2002·Journal of Environmental Monitoring : JEM·Mika ToivolaAino Nevalainen
Oct 1, 1996·Journal of the Air & Waste Management Association·Joel SchwartzLucas M Neas

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Citations

Oct 16, 2007·Journal of Toxicology and Environmental Health. Part a·V LiebersTh Brüning
Dec 20, 2005·Occupational and Environmental Medicine·K Radon
Mar 31, 2009·International Journal of Molecular Sciences·Anne S Halstensen
Feb 27, 2016·International Journal of Hygiene and Environmental Health·Olivier SchlosserCatherine Debeaupuis
Jan 21, 2015·Indoor Air·A NevalainenA Hyvärinen
May 6, 2016·Environmental Research·Randi Jacobsen BertelsenCecilie Svanes
Nov 30, 2006·Journal of Environmental Monitoring : JEM·Anne Straumfors HalstensenSonja Sletner Klemsdal
Apr 6, 2006·American Journal of Industrial Medicine·Verena LiebersMonika Raulf-Heimsoth
Nov 9, 2010·Journal of Occupational and Environmental Hygiene·M W NonnenmannJ L Levin

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