Working towards personalization in medicine: main obstacles to reaching this vision from today's perspective

Personalized Medicine
Lada LeyensAngela Brand

Abstract

Rapid advances in 'omics' sciences and technologies have elevated the relevance of personalized medicine. This article reviews the current advances in the application of personalized medicine, outlines and summarizes the key areas that still need to be addressed and gives recommendations in this direction. Eighteen relevant high-level reports on personalized medicine were reviewed in order to identify the gaps and needs that are present for the implementation of personalized medicine. We identify 12 key areas that represent the main obstacles on the road towards the personalization of medicine and divide these 12 key areas into four domains, namely: scientific research and stakeholder collaboration; translational tools; regulations and systematic early dialog with regulators; and uptake into healthcare systems. All of the evaluated reports agree on the imperative need for intensive collaboration among all stakeholders with early active participation and changes in the current healthcare infrastructure.

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Citations

Sep 1, 2014·Personalized Medicine·George P Patrinos, Barbara Prainsack
Jun 4, 2015·Drug Metabolism and Personalized Therapy·Francesca MalentacchiUNKNOWN European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) – European Society of Pharmacogenomics and Personal
May 23, 2015·Clinical Chemistry and Laboratory Medicine : CCLM·Francesca MalentacchiUNKNOWN European Society of Pharmacogenomics and Personalised Therapy (ESPT) Joint Working Group on Personalized Laboratory Medicine
Jan 1, 2017·Personalized Medicine·Sebastian Schee Genannt HalfmannAngela Brand
Jul 20, 2016·BMC Medical Ethics·Giovanni De Grandis, Vidar Halgunset

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