Workplace drug testing, different matrices different objectives

Drug Testing and Analysis
Lolita TsanaclisAlice A M Chasin

Abstract

Drug testing is used by employers to detect drug use by employees or job candidates. It can identify recent use of alcohol, prescription drugs, and illicit drugs as a screening tool for potential health and safety and performance issues. Urine is the most commonly used sample for illicit drugs. It detects the use of a drug within the last few days and as such is evidence of recent use; but a positive test does not necessarily mean that the individual was impaired at the time of the test. Abstention from use for three days will often produce a negative test result. Analysis of hair provides a much longer window of detection, typically 1 to 3 months. Hence the likelihood of a falsely negative test using hair is very much less than with a urine test. Conversely, a negative hair test is a substantially stronger indicator of a non-drug user than a negative urine test. Oral fluid (saliva) is also easy to collect. Drugs remain in oral fluid for a similar time as in blood. The method is a good way of detecting current use and is more likely to reflect current impairment. It offers promise as a test in post-accident, for cause, and on-duty situations. Studies have shown that within the same industrial settings, hair testing can detect t...Continue Reading

References

Apr 21, 1990·Lancet·C Brewer
Jan 5, 1995·Forensic Science International : Synergy·R L DuPont, W A Baumgartner
Jan 17, 1997·Forensic Science International : Synergy·M RotheJ Hunger
Jan 1, 1997·International Journal of Legal Medicine·C JuradoM Repetto
Feb 26, 2000·Forensic Science International : Synergy·R Wennig
Feb 26, 2000·Forensic Science International : Synergy·R C KellyJ A Bourland
Sep 29, 2004·Forensic Science International : Synergy·Thomas CairnsWilliam Thistle
Apr 21, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Fritz Pragst, Marie A Balikova
May 19, 2006·Forensic Science International : Synergy·Rachel C Irving, Stuart J Dickson
Jul 7, 2007·Forensic Science International : Synergy·Lolita Tsanaclis, John F C Wicks
Nov 6, 2007·Forensic Science International : Synergy·Lolita Tsanaclis, John F C Wicks
Nov 9, 2007·Journal of Analytical Toxicology·Edward J ConeLolita Tsanaclis
Sep 12, 2009·Clinical Chemistry·Wendy M Bosker, Marilyn A Huestis
May 4, 2011·Drug Testing and Analysis·Gail CooperUNKNOWN European Workplace Drug Testing Society

❮ Previous
Next ❯

Citations

Aug 21, 2013·Analytical and Bioanalytical Chemistry·Sebastien AnizanMarilyn A Huestis
Aug 5, 2015·Clinical Pharmacokinetics·Pieter M M De KeselChristophe P Stove
Oct 23, 2015·Journal of Forensic and Legal Medicine·Valérie Baillif-CouniouAnne-Laure Pelissier-Alicot
May 13, 2014·Drug Testing and Analysis·Ronald AgiusThomas Nadulski
Jan 30, 2015·Therapeutic Drug Monitoring·María Del Mar Ramírez FernándezNele Samyn
Nov 11, 2014·Bioanalysis·Sarah M R WilleThomas Kraemer
Jul 22, 2014·Bioanalysis·Shanlin FuUnnikrishnan Kuzhiumparambil
Jul 17, 2013·Journal of Cardiovascular Medicine·Matteo AnselminoFiorenzo Gaita
May 9, 2019·American Journal of Pharmaceutical Education·Patricia L DarbishirePriya B Patel
Apr 1, 2020·Journal of Analytical Toxicology·Lolita TsanaclisJohn Wicks
Dec 18, 2020·Clinica Chimica Acta; International Journal of Clinical Chemistry·Kenichi Tamama

❮ Previous
Next ❯

Related Concepts

Related Feeds

Addiction

This feed focuses mechanisms underlying addiction and addictive behaviour including heroin and opium dependence, alcohol intoxication, gambling, and tobacco addiction.