PMID: 11901642Mar 21, 2002Paper

World War I may have allowed the emergence of "Spanish" influenza

The Lancet Infectious Diseases
J S OxfordN P A S Johnson

Abstract

The 1918 influenza pandemic caused 40 million deaths, and so dwarfed in mortality and morbidity the preceding pandemic of 1889 and the 1957 and 1968 pandemics. In retrospect, much can be learnt about the source, the possible subterranean spread of virus, and the genetic basis of virulence. The World Health Organization has urged every nation to prepare a pandemic plan for the first global outbreak of the 21st century. We present an appraisal of epidemiological and mortality evidence of early outbreaks of respiratory disease in France and the UK in the years 1915 to 1917. Certain of these earlier focal outbreaks--called epidemic bronchitis rather than influenza--occurred during the winter months when influenza was known to be in circulation, and presented with a particular heliotrope cyanosis that was so prominent in the clinical diagnosis in the world pandemic outbreak of 1918-1919 (the Great Pandemic). The outbreaks in army camps at Etaples in France and Aldershot in the UK in 1916-1917 caused very high mortality in 25-35 year olds. Increased deaths from bronchopneumonia and influenza were also recorded in England. We deduce that early focal outbreaks of influenza-like disease occurred in Europe and on the balance of probabili...Continue Reading

References

Aug 1, 1994·European Journal of Epidemiology·P Morgan-Capner
Mar 21, 1997·Science·J K TaubenbergerT G Fanning
Feb 17, 1999·Proceedings of the National Academy of Sciences of the United States of America·A H ReidJ K Taubenberger
Mar 4, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R G Webster
Oct 8, 1999·Emerging Infectious Diseases·M I MeltzerK Fukuda
Nov 4, 2000·The New England Journal of Medicine·F G HaydenUNKNOWN Zanamivir Family Study Group
Aug 4, 2001·Trends in Genetics : TIG·A R Samuel, N J Knowles

❮ Previous
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Citations

Aug 13, 2009·JAMA : the Journal of the American Medical Association·David M Morens, Jeffery K Taubenberger
Jan 18, 2013·Epidemiology and Infection·G D ShanksM Smallman-Raynor
Dec 14, 2006·The Journal of Infectious Diseases·Adolfo Garcia-Sastre, Richard J Whitley
Jul 26, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Antoni TrillaCarolyn Daer
Dec 22, 2006·Journal of Virology·Eric LofgrenE N Naumova
Mar 29, 2003·BMJ : British Medical Journal·Maria Zambon, Karl G Nicholson
Feb 24, 2006·Emerging Infectious Diseases·Jeffery K Taubenberger, David M Morens
Apr 14, 2006·Emerging Infectious Diseases·Jeffery K Taubenberger, David M Morens
Jun 8, 2007·Emerging Infectious Diseases·Akihiko KawanaKoichiro Kudo
Mar 16, 2005·The Lancet Infectious Diseases·John S Oxford
Apr 4, 2014·BMC Medicine·Delan DevakumarJonathan C K Wells
Feb 11, 2011·Current Infectious Disease Reports·Guillermo Domínguez-CheritJose Angel Cordova-Villalobos
Feb 9, 2013·BMC Public Health·José María MayoralUNKNOWN CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain
Nov 7, 2015·Journal of the Chinese Medical Association : JCMA·G Dennis Shanks
Jan 21, 2010·Journal of Theoretical Biology·Gui-Quan SunBai-Lian Li
Apr 15, 2008·American Journal of Preventive Medicine·Seung-Eun LeePaul Ciminera
May 21, 2009·Influenza and Other Respiratory Viruses·Séverine AnsartAlain-Jacques Valleron
Sep 27, 2013·Influenza and Other Respiratory Viruses·Carol JosephNahoko Shindo
Jul 1, 2014·Influenza and Other Respiratory Viruses·Peter C Wever, Leo van Bergen
Aug 15, 2015·Influenza and Other Respiratory Viruses·Jens W LevyIn-Kyu Yoon
Jul 12, 2005·Antiviral Chemistry & Chemotherapy·Eddy Littler, Bo Oberg
Mar 15, 2018·Neurosurgery·Zachary S HubbardAllan D Levi
Sep 25, 2007·Minnesota Medicine·Linda Amaikwu-RushingMargaret Dexheimer Pharris
Nov 14, 2018·Influenza and Other Respiratory Viruses·Juan CristinaAdela Pellegrino
Sep 12, 2012·Theoretical Biology & Medical Modelling·Ray Greek, Mark J Rice
Jul 12, 2019·Internal Medicine Journal·G Dennis Shanks
Mar 21, 2007·British Journal of Hospital Medicine·John Oxford
Feb 2, 2008·American Journal of Physiology. Gastrointestinal and Liver Physiology·Shohreh F FarzanDavid J Robbins
Mar 4, 2018·Die Naturwissenschaften·Carmelo Peter Bonsignore, Umberto Bernardo
Dec 25, 2019·Cold Spring Harbor Perspectives in Medicine·Jeffery K Taubenberger, David M Morens
Jul 12, 2017·Frontiers in Microbiology·Denise E MorrisStuart C Clarke
Jan 1, 2010·Public Health Reviews·Antoine Flahault, Patrick Zylberman
Oct 26, 2018·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Joaquim Ruiz
Jul 26, 2019·Science Translational Medicine·Jeffery K TaubenbergerDavid M Morens
Jan 1, 2005·Ecosystems·Colin D ButlerHillel S Koren
Oct 24, 2018·Frontiers in Cellular and Infection Microbiology·Kirsty R ShortCarolien E van de Sandt

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