WormBase: a comprehensive resource for nematode research

Nucleic Acids Research
Todd W HarrisPaul W Sternberg


WormBase (http://www.wormbase.org) is a central data repository for nematode biology. Initially created as a service to the Caenorhabditis elegans research field, WormBase has evolved into a powerful research tool in its own right. In the past 2 years, we expanded WormBase to include the complete genomic sequence, gene predictions and orthology assignments from a range of related nematodes. This comparative data enrich the C. elegans data with improved gene predictions and a better understanding of gene function. In turn, they bring the wealth of experimental knowledge of C. elegans to other systems of medical and agricultural importance. Here, we describe new species and data types now available at WormBase. In addition, we detail enhancements to our curatorial pipeline and website infrastructure to accommodate new genomes and an extensive user base.


Oct 6, 1997·Endocrinology and Metabolism Clinics of North America·M C Riddle
Dec 16, 1998·Science·UNKNOWN C. elegans Sequencing Consortium
Aug 15, 2002·Bioinformatics·Boris Lenhard, Wyeth W Wasserman
Oct 9, 2002·Genome Research·Lincoln D SteinSuzanna Lewis
Nov 19, 2003·PLoS Biology·Lincoln D SteinRobert H Waterston
May 8, 2004·Nature Reviews. Genetics·Wyeth W Wasserman, Albin Sandelin
Dec 31, 2005·Nucleic Acids Research·Heng LiRichard Durbin
Aug 9, 2006·BMC Bioinformatics·David ChenPaul W Sternberg
Nov 14, 2006·Nucleic Acids Research·Lisa R GirardMartin Chalfie
Sep 22, 2007·Science·Elodie GhedinAlan L Scott
Dec 7, 2007·Nucleic Acids Research·Ann-Charlotte BerglundErik L L Sonnhammer
Jul 29, 2008·Nature Biotechnology·Pierre AbadPatrick Wincker
Sep 24, 2008·Proceedings of the National Academy of Sciences of the United States of America·Charles H OppermanEric Windham
Sep 27, 2008·Current Protocols in Bioinformatics·Huey-Ling Kao, Kristin C Gunsalus
Nov 5, 2008·Nucleic Acids Research·Lisa MatthewsPeter D'Eustachio
Nov 27, 2008·Nucleic Acids Research·T J P HubbardP Flicek

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Jul 21, 2012·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Georgios V GkoutosRobert Hoehndorf
Jan 17, 2012·Nature Genetics·Neil D YoungRobin B Gasser
Apr 27, 2010·Nature Methods·Christian Frøkjaer-JensenErik M Jorgensen
Jul 27, 2012·Briefings in Bioinformatics·Chang F QuoGil Alterovitz
May 6, 2011·Database : the Journal of Biological Databases and Curation·G W WilliamsJ Spieth
Jun 28, 2011·Database : the Journal of Biological Databases and Curation·Steve FischerChristian J Stoeckert
Sep 21, 2011·Database : the Journal of Biological Databases and Curation·Junjun ZhangArek Kasprzyk
Sep 21, 2011·Database : the Journal of Biological Databases and Curation·Jonathan M GubermanArek Kasprzyk
Oct 1, 2011·Database : the Journal of Biological Databases and Curation·Stephen P FicklinDoreen Main
Mar 22, 2012·Database : the Journal of Biological Databases and Curation·Esther T Chan, J Michael Cherry
Mar 22, 2012·Database : the Journal of Biological Databases and Curation·Nicholas A StoverTheodore G Clark
Jul 3, 2013·Database : the Journal of Biological Databases and Curation·Chunguang LiangThomas Dandekar
Oct 29, 2013·Database : the Journal of Biological Databases and Curation·Lacey-Anne SandersonDorrie Main
Feb 28, 2014·Database : the Journal of Biological Databases and Curation·Janos X BinderLars Juhl Jensen
Aug 24, 2011·Genome Biology and Evolution·Kiyoshi EzawaNaruya Saitou
Aug 24, 2011·Genome Biology and Evolution·Lisa G McFerrin, William R Atchley
Nov 3, 2010·Nucleic Acids Research·Kate B CookTimothy R Hughes
Nov 13, 2010·Nucleic Acids Research·Chris StarkMike Tyers
May 25, 2010·Nucleic Acids Research·Barry MooreKaren Eilbeck
Sep 30, 2010·Nucleic Acids Research·Andrei L TurinskyShoshana J Wodak
Oct 12, 2010·Nucleic Acids Research·Ruth L SealElspeth A Bruford
Nov 30, 2011·Nucleic Acids Research·Emily C DimmerRolf Apweiler
Dec 6, 2011·Nucleic Acids Research·Eugene KolkerNatali Kolker
May 31, 2011·Nucleic Acids Research·Mario FasoldSteve Hoffmann
Nov 8, 2011·Nucleic Acids Research·Sujai KumarMark Blaxter
Nov 10, 2011·Nucleic Acids Research·Paul J KerseyEwan Birney
Nov 15, 2011·Nucleic Acids Research·Sergio ContrinoGos Micklem
Nov 10, 2011·Nucleic Acids Research·Karen YookPaul W Sternberg
Nov 15, 2011·Nucleic Acids Research·Erich J BakerElissa J Chesler
May 31, 2012·Nucleic Acids Research·Timothy PadawerDegeng Wang
Oct 29, 2010·Genome Research·Ali MortazaviPaul W Sternberg
Dec 24, 2010·Genome Research·Arun K RamaniAndrew G Fraser
Apr 18, 2012·Genome Research·John Isaac MurrayRobert H Waterston
May 3, 2013·Genome Research·Taro Leo SaitoShinichi Morishita
Jun 5, 2010·Science·Marco MangoneJohn K Kim
Jan 26, 2011·BMC Bioinformatics·Gary SchindelmanPaul W Sternberg
Jul 5, 2006·BMC Bioinformatics·Chaochun Wei, Michael R Brent

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Methods Mentioned

Illumina sequencing

Software Mentioned

SPELL ( Serial Patterns of Expression Levels Locator )
Ensembl Compara

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