Wound healing in Behçet's syndrome

International Journal of Dermatology
M C MatH Yazici

Abstract

Because there is an increased inflammatory response to trauma, particularly of the skin, in patients with Behçet's syndrome (BS), an alteration in wound healing in BS is expected. The aim of this study was to investigate the healing features of punch biopsy wounds in BS and acne vulgaris (AV) patients used as controls. Full-thickness skin punch biopsies (4 mm) were taken from the hairless sites of the non-dominant forearms in 20 BS and 20 AV patients. Each patient was examined on days 1, 2, 3, 4, 5, 8, and 10, and the biopsy wound area and induration were marked on sterile glass slides. Other inflammatory changes, such as suppuration and pain, were also recorded. No antiseptic solutions or ointment, except saline, were used. The wound area healed similarly in both groups (p > 0.05). Thirteen (65%) BS patients had erythematous haloes around the wound on the first day. The number of patients presenting inflammatory changes reached 18 (90%) on the second day in the BS group. The area of erythema around the wound in BS patients was significantly greater than that in AV patients (5; 25%). It gradually decreased day by day. Purulent changes were observed in four BS patients on day 1, and induration around the biopsy wound in six pati...Continue Reading

Citations

May 17, 2006·International Journal of Dermatology·M Cem MatHasan Yazici
Feb 26, 1999·The Journal of Urology·B CetinelH Yazici
Apr 12, 2008·Archives of Dermatological Research·Alena SvobodováJitka Vostálová
Oct 24, 2006·The Journal of Immunology : Official Journal of the American Association of Immunologists·Melike MelikogluStephen Oliver
Feb 18, 2004·The Breast : Official Journal of the European Society of Mastology·M UludağM Içen
Jun 12, 2021·Frontiers in Medicine·Tulin Ergun

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