Wound healing potential of Elaeis guineensis Jacq leaves in an infected albino rat model.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Sreenivasan SasidharanRajoo Amala

Abstract

Elaeis guineensis Jacq (Arecaceae) is one of the plants that are central to the lives of traditional societies in West Africa. It has been reported as a traditional folkloric medicine for a variety of ailments. The plant leaves are also used in some parts of Africa for wound healing, but there are no scientific reports on any wound healing activity of the plant. To investigate the effects of E. guineensis leaf on wound healing activity in rats. A phytochemical screening was done to determine the major phytochemicals in the extract. The antimicrobial activity of the extract was examined using the disk diffusion technique and broth dilution method. The wound healing activity of leaves of E. guineensiswas studied by incorporating the methanolic extract in yellow soft paraffin in concentration of 10% (w/w). Wound healing activity was studied by determining the percentage of wound closure, microbial examination of granulated skin tissue and histological analysis in the control and extract treated groups. Phytochemical screening reveals the presence of tannins, alkaloids, steroids, saponins, terpenoids, and flavonoids in the extract. The extract showed significant activity against Candida albicans with an MIC value of 6.25 mg/mL. The...Continue Reading

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Citations

Apr 10, 2013·Asian Pacific Journal of Tropical Biomedicine·Soundararajan Vijayarathna, Sreenivasan Sasidharan
Feb 9, 2012·International Journal of Molecular Sciences·Sreenivasan SasidharanLachimanan Yoga Latha
Feb 26, 2014·Journal of Ethnopharmacology·Namrita Lall, Navneet Kishore
Sep 18, 2013·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Xana Raquel OrtolanFátima de Campos Buzzi
Jul 23, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Aleksandra BudzyńskaBarbara Różalska
Aug 12, 2015·Colloids and Surfaces. B, Biointerfaces·Jaewook LeeJaebeom Lee
Oct 2, 2015·BMC Complementary and Alternative Medicine·Eshetu MulisaEphrem Engidawork
Aug 19, 2015·BMC Complementary and Alternative Medicine·Michael GebrehiwotFranz Bucar
Aug 2, 2014·Biochemical Pharmacology·Limei WangAtanas G Atanasov
Aug 12, 2016·Biological Reviews of the Cambridge Philosophical Society·Claudia DislichKerstin Wiegand
Apr 28, 2012·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Soundararajan VijayarathnaSreenivasan Sasidharan
Jun 14, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mehmet Evren OkurFatih Demirci
Jan 26, 2017·Evidence-based Complementary and Alternative Medicine : ECAM·Qi ZengFu Wang
Feb 26, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Richard KomakechYoungmin Kang
Apr 22, 2021·Microscopy Research and Technique·Saima AliRaees Khan

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