Wound infection after colostomy closure for imperforate anus in children: utility of preoperative oral antibiotics

Journal of Pediatric Surgery
Francine D BrecklerDeborah F Billmire

Abstract

There is little published data on the efficacy of surgical infection prophylaxis in children. The purpose of this study was to assess wound infection rate in children undergoing colostomy closure for imperforate anus and evaluate the impact of bowel preparation and antibiotics. Children younger than 18 years with imperforate anus who had a colostomy closure between January 1996 and December 2007 were identified. Data collected included demographics, bowel preparation, antibiotics, operative details, and postoperative infections. Comparison of mechanical bowel preparation and intravenous antibiotics with and without oral antibiotics was compared using chi(2) tests. Significance was defined as P < .05. A total of 118 patients were identified. Primary skin closure was done in 97%. Mechanical bowel preparation was used in 93%, intravenous antibiotics in 97%, and oral preoperative antibiotics in 52%. Wound infections occurred in 14% (n = 17). The addition of oral antibiotics to the standard regimen of mechanical bowel preparation with intravenous antibiotics did not alter infection rate (13% versus 17%, P = .64). Wound infection in children undergoing elective colostomy closure for imperforate anus was 14%. Infection rate was not af...Continue Reading

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Citations

Jan 17, 2012·Journal of Pediatric Surgery·Katherine SerrurierGerald Gollin
Oct 1, 2011·Advances in Surgery·Danielle FritzeDarrell A Campbell
Mar 25, 2016·The Indian Journal of Surgery·Yusuf Hakan Çavuşoğluİsmet Faruk Özgüner
Oct 22, 2018·Pediatric Surgery International·Maarten Janssen LokAgostino Pierro
Apr 1, 2015·Journal of Pediatric Gastroenterology and Nutrition·Jennifer H AldrinkBenedict C Nwomeh
Nov 11, 2019·Journal of Pediatric Surgery·Hira AhmadMarc A Levitt

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