Wound infection prophylaxis in pediatric acute appendicitis: a 26-year prospective study

Journal of Pediatric Surgery
Sigmund H Ein, Anthony Sandler

Abstract

The purpose of this study was to determine the best wound infection prophylaxis in pediatric acute appendicitis. From 1969 to 1995 inclusive, 453 consecutive pediatric patients at the same children's hospital had an appendix with acute inflammation (acute appendicitis) removed by the same staff surgeon and his resident. The stump was not inverted, and chromic catgut was used throughout. No intraperitoneal antibiotics, irrigation, or drains were used, and the skin closure was with silk sutures initially and then with staples since 1986. The infants and children were divided into 6 consecutive groups of 52 to 96 patients, with each group lasting 2 to 5 years. The wound treatment groups were as follows: no treatment, drain or pack, drain or pack plus antibiotic powder, antibiotic powder, preoperative intravenous antibiotic plus antibiotic powder, and preoperative intravenous antibiotic. The wound Penrose drain, one half-inch gauze pack, and/or antibiotic powder (ampicillin, 1977-1981; cefoxitin, 1982-1995) were all placed in the subcutaneous space. There were a total of 50 (11%) wound infections (pus) that occurred between 4 and 40 days when no antibiotic powder was used and 2 to 14 days with antibiotic powder. In all 6 groups of ...Continue Reading

References

May 1, 1992·Journal of Pediatric Surgery·F KizilcanA Hiçsönmez
Feb 1, 1974·Journal of Pediatric Surgery·B ShandlingS K Bandi
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Jul 4, 2002·American Journal of Surgery·Kenneth S HelmerDavid W Mercer
Jul 5, 2002·World Journal of Surgery·Gerald T McGrealH Paul Redmond

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Citations

Mar 7, 2007·Pediatric Surgery International·Adnan AslanMustafa Melikoglu
Mar 28, 2008·Surgical Infections·Evan P NadlerUNKNOWN Therapeutic Agents Committee of the Surgical Infection Society
Dec 22, 2017·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Cristen N LitzNicole M Chandler
Nov 4, 2010·Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society·S L PauniahoO Pajulo
Oct 22, 2016·World Journal of Surgery·Luis Angel Medina AndradeIsrael Gonzalez Gonzalez
Jul 11, 2019·Revista paulista de pediatria : orgão oficial da Sociedade de Pediatria de São Paulo·Fátima Maria Castelo Branco RoqueEdna Maria Camelo Chaves

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