Wound sterilization: CO2 laser versus iodine

British Journal of Plastic Surgery
M M al-QattanD J Hoban

Abstract

Control of infection in a surgical wound remains a challenge, especially if further surgery in the area is needed. This study was designed to compare the effectiveness of sterilization of a standard experimental infected wound by surgical skin preparation (Betadine) as compared to treatment with the CO2 laser. Standard wounds (5 x 6 cm) were created superficial to the panniculus carnosus on each flank of 37 adult male New Zealand rabbits. Each wound was infected with a standard dose of Pseudomonas aeruginosa. All wounds became grossly infected. On the third day one flank wound was treated with the CO2 laser, the other with the Betadine solution, and a punch biopsy (4 mm) was taken from each wound for quantitative bacterial counts. Less than 10% of the laser-treated wounds grew Pseudomonas, whereas nearly 40% of the iodine-treated wounds remained infected (P less than 0.005). Our early clinical experience using the CO2 laser for the sterilization of infected wounds is also reported.

Citations

Jan 1, 1994·Lasers in Surgery and Medicine·N TalebzadehM P Fried
Jan 1, 1993·Aesthetic Plastic Surgery·P B Fodor
Oct 1, 1992·British Journal of Plastic Surgery·M F Stranc, F W Yang
Aug 8, 2002·Journal of Clinical Laser Medicine & Surgery·Antonio Luiz B PinheiroMarcos André Matos De Oliveira
Dec 1, 2006·Dermatology : International Journal for Clinical and Investigative Dermatology·Karin SartoriusMaria Hedberg
Sep 27, 2019··Glenn D. WardDuncan E. Stewart-Tull

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