WRKY55 transcription factor positively regulates leaf senescence and the defense response by modulating the transcription of genes implicated in the biosynthesis of reactive oxygen species and salicylic acid in Arabidopsis.

Development
Yiqiao WangYuan-Qing Jiang

Abstract

Reactive oxygen species (ROS) and salicylic acid (SA) are two factors regulating leaf senescence and defense against pathogens. However, how a single gene integrates both ROS and SA pathways remains poorly understood. Here, we show that Arabidopsis WRKY55 transcription factor positively regulates ROS and SA accumulation, and thus leaf senescence and resistance against the bacterial pathogen Pseudomonas syringae WRKY55 is predominantly expressed in senescent leaves and encodes a transcriptional activator localized to nuclei. Both inducible and constitutive overexpression of WRKY55 accelerates leaf senescence, whereas mutants delay it. Transcriptomic sequencing identified 1448 differentially expressed genes, of which 1157 genes are upregulated by WRKY55 expression. Accordingly, the ROS and SA contents in WRKY55-overexpressing plants are higher than those in control plants, whereas the opposite occurs in mutants. Moreover, WRKY55 positively regulates defense against P. syringae Finally, we show that WRKY55 activates the expression of RbohD, ICS1, PBS3 and SAG13 by binding directly to the W-box-containing fragments. Taken together, our work has identified a new WRKY transcription factor that integrates both ROS and SA pathways to r...Continue Reading

References

Feb 12, 1998·Plant Physiology
Aug 26, 1998·Proceedings of the National Academy of Sciences of the United States of America·N AartsJ E Parker
Mar 9, 1999·The Plant Journal : for Cell and Molecular Biology·S J Clough, A F Bent
Sep 6, 2000·The Plant Journal : for Cell and Molecular Biology·K MorrisV Buchanan-Wollaston
Nov 9, 2000·The Plant Journal : for Cell and Molecular Biology·J DewdneyF M Ausubel
Jan 5, 2002·Proceedings of the National Academy of Sciences of the United States of America·Miguel Angel TorresJonathan D G Jones
May 10, 2002·Genes & Development·Silke Robatzek, Imre E Somssich
Aug 1, 1995·Plant Physiology·J. LeonI. Raskin
Feb 27, 2003·Plant Molecular Biology·Jixin DongZhixiang Chen
Nov 18, 2003·The Plant Journal : for Cell and Molecular Biology·Shimon GepsteinMichal Bassani
Sep 1, 2004·Current Opinion in Plant Biology·Bekir Ulker, Imre E Somssich
Jun 9, 2005·Current Opinion in Plant Biology·Miguel Angel Torres, Jeffery L Dangl
Dec 14, 2005·Current Topics in Developmental Biology·Yongfeng Guo, Susheng Gan
Dec 21, 2006·Annual Review of Plant Biology·Pyung Ok LimHong Gil Nam
Jul 27, 2007·The Plant Journal : for Cell and Molecular Biology·Thomas S NühseScott C Peck
Sep 20, 2008·Plant Biology·S BalazadehB Mueller-Roeber
Apr 30, 2009·Annual Review of Phytopathology·A Corina VlotDaniel F Klessig
Mar 23, 2010·Trends in Plant Science·Paul J RushtonQingxi J Shen
Mar 2, 2011·Journal of Experimental Botany·Mariana Rivas-San Vicente, Javier Plasencia
Apr 14, 2011·Plant, Cell & Environment·Nobuhiro SuzukiGad Miller
Aug 25, 2011·Current Opinion in Plant Biology·Nobuhiro SuzukiRon Mittler
Oct 20, 2011·The Plant Journal : for Cell and Molecular Biology·Kewei ZhangSu-Sheng Gan
Jan 24, 2012·Journal of Experimental Botany·Sébastien BesseauE Tapio Palva
Jan 1, 2002·The Arabidopsis Book·Fumiaki KatagiriSheng Yang He
Feb 4, 2012·The Arabidopsis Book·D'Maris Amick DempseyDaniel F Klessig

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