PMID: 2121806Nov 1, 1990Paper

Xanthoma disseminatum and Waldenström's macroglobulinemia

Journal of the American Academy of Dermatology
M E GoodenbergerZsolt B Argenyi

Abstract

A 71-year-old woman had a 7-month history of multiple asymptomatic papules on the upper part of the body. The clinical picture and histopathologic findings confirmed the diagnosis of xanthoma disseminatum. Further studies revealed Waldenström's macroglobulinemia. Treatment with chlorambucil and prednisone led to a dramatic reduction in her paraprotein level. In addition, cutaneous lesions improved and new lesions stopped appearing. Treatment of selected papules by cryotherapy or intralesional corticosteroid injection provided further improvement. This case is notable because (1) it is the first report of xanthoma disseminatum in a patient with Waldenström's macroglobulinemia and (2) there was an unusually good response to therapy.

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Citations

Dec 21, 2002·International Journal of Dermatology·Rudolf A Rupec, Martin Schaller
Dec 14, 1999·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·B G CarpoJ M Grevelink
Aug 1, 1992·The British Journal of Dermatology·S E Whitmore
May 1, 1993·Clinical and Experimental Dermatology·L TörökG Szabó
Aug 26, 2009·International Journal of Dermatology·Ashok Ghorpade
May 15, 2010·International Journal of Dermatology·Masahiro OkaChikako Nishigori
Nov 7, 2008·International Journal of Dermatology·Shehu M YusufAminu Z Mohammed
May 1, 1992·Journal of the American Academy of Dermatology·B S DarwinE A Olsen
Feb 15, 2018·International Journal of Dermatology·Ramin FathiRyan Stevens
Mar 12, 2008·Journal of Cutaneous Pathology·Franco RongiolettiAlfredo Rebora
Oct 6, 2005·Dermatology : International Journal for Clinical and Investigative Dermatology·Sonia GiménezRamon M Pujol
Jul 19, 2003·The Australasian Journal of Dermatology·Sujay KhandpurNikhil Tandon
May 27, 2011·Dermatology : International Journal for Clinical and Investigative Dermatology·H Y ParkS J Yun

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