XEN glaucoma treatment system in the management of refractory glaucomas: a short review on trial data and potential role in clinical practice

Clinical Ophthalmology
A De GregorioS Morselli

Abstract

The recent development of new devices that are significantly less invasive, collectively termed minimally invasive glaucoma surgery, offers new perspective of intraocular pressure reduction with less risk, short operating times, and rapid recovery. The aim of this work is to provide a panoramic review of the currently published clinical data to assess the potential role of XEN gel stent (Allergan PLC, Irvine, CA, USA) in the management of glaucoma, which is the only filtering minimally invasive glaucoma surgery device that allows the subconjunctival filtration. The ab interno placement of the XEN gel stent offers an alternative for lowering intraocular pressure in refractory glaucoma as a final step, and in patients intolerant to medical therapy as an early surgical approach with minimum conjunctival tissue disruption, restricted flow to avoid hypotony, and long-term safety.

Citations

May 17, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·María Teresa Marcos ParraJuan José Pérez Santonja
Feb 3, 2019·Journal of Cataract and Refractive Surgery·Tanner J FergusonJohn P Berdahl
Dec 27, 2018·Journal of Glaucoma·Francesco StringaVikas Shankar
Feb 13, 2020·Journal of Cataract and Refractive Surgery·Antonio M FeaFrancesco Oddone
Mar 19, 2020·Acta Ophthalmologica·Filipa Jorge TeixeiraLuís Abegão Pinto
May 15, 2020·European Journal of Ophthalmology·Chih-Hung Kuo
Aug 20, 2020·European Journal of Ophthalmology·Cosme Lavin-DapenaIsabel Mogollón
Oct 1, 2020·European Journal of Ophthalmology·Myrta LipperaCarlo Cagini
Dec 1, 2018·Vestnik oftalmologii·S Yu Petrov, A V Volzhanin
Jan 3, 2021·International Ophthalmology·Aritz Urcola, Gonzaga Garay-Aramburu
Jan 22, 2021·European Journal of Ophthalmology·Martina MenchiniMichele Figus
Oct 23, 2020·Medical Humanities·Jill Felicity Durey
Mar 7, 2020·Journal of Cataract and Refractive Surgery·Antonio M FeaFrancesco Oddone
Mar 23, 2021·Journal of Ophthalmology·Carlo Alberto CutoloMichele Iester
Oct 1, 2019·Journal of Current Glaucoma Practice·Zaria C AliVikas Shankar
Jan 27, 2019·Journal français d'ophtalmologie·J BuffaultA Labbé
Apr 30, 2021·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Sheng Yang LimBryan Chin Hou Ang
Jun 15, 2021·Ocular Immunology and Inflammation·Hanna FaberBogomil Voykov
Nov 25, 2021·Journal of Materials Science. Materials in Medicine·Brandon W KaoEydie G Miller-Ellis

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Methods Mentioned

BETA
dissection
confocal microscopy

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