PMID: 11335120May 4, 2001Paper

Xenopus frizzled-5: a frizzled family member expressed exclusively in the neural retina of the developing eye

Mechanisms of Development
S Sumanas, S C Ekker

Abstract

We have isolated a new Wnt receptor frizzled family member from Xenopus laevis, Xenopus frizzled-5 (Xfz5), a likely ortholog of human frizzled-5. Based on Northern and whole-mount in situ hybridization data, Xfz5 is first detected at the late neurula stage in retinal primordia. Throughout the tailbud stage Xfz5 is expressed exclusively in the neural retina within the optic vesicles. During tadpole stage Xfz5 expression becomes restricted to the ciliary marginal zone. This highly restrictive expression pattern makes Xfz5 an excellent marker for neural retinal tissue.

References

Aug 14, 1999·Mechanisms of Development·G N Wheeler, S Hoppler
Aug 24, 1999·Cell·M E ZuberW A Harris
Sep 24, 1999·Mechanisms of Development·M A Deardorff, P S Klein
Mar 8, 2000·Mechanisms of Development·X ZhouP Gruss

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Citations

Aug 28, 2003·Developmental Biology·Blue B Lake, Kenneth R Kao
Mar 28, 2008·Development, Growth & Differentiation·Fumi Kubo, Shinichi Nakagawa
Feb 19, 2009·Molecular and Cellular Biology·Hyunjoon KimJin-Kwan Han
Apr 28, 2005·Developmental Neuroscience·Terence J Van Raay, Monica L Vetter
May 21, 2008·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Carole J BurnsSabine Fuhrmann
Jul 20, 2002·Mechanisms of Development·Eun-Jung JinCarol A Erickson
Nov 1, 2005·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Valentina M Fokina, Elena I Frolova
May 2, 2003·Journal of Cell Science·Pilar EstevePaola Bovolenta

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