PMID: 8593316Oct 1, 1995Paper

Xenotransplantation and high tumorigenicity of feline tumors in SCID mice

The Journal of Veterinary Medical Science
K MaruoT Nomura

Abstract

Nine feline tumors resected at surgery were subcutaneously xenotransplanted into SCID mice. The primary take rate of the benign and malignant tumors was 50% (1/2) and 100% (7/7) respectively. Six of the eight primary tumor xenografts transplanted and grown in the first recipient were successfully transplanted serially. One feline mammary adenocarcinoma xenograft metastasized to the lung of a SCID mouse. The primary take rate of feline tumors to SCID mice was high and the established xenografts appear to be valuable tools for investigating growth and metastasis mechanisms, and various therapies for feline neoplasms.

Citations

Dec 21, 2002·American Journal of Veterinary Research·Deborah A GrossmanSanford H Barsky
Oct 9, 1998·The Journal of Veterinary Medical Science·J S MuleyaS Nakama
Aug 28, 2021·Animals : an Open Access Journal From MDPI·Hsiao-Li ChuangYu-Chih Wang

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