Xiangbin prescription for the recovery of gastrointestinal function after abdominal surgery (the XBPRS trial): study protocol for a randomized controlled trial

Trials
Huachan GanZhiqiang Chen

Abstract

Most patients who undergo abdominal surgery recover bowel movements within a week; however, some suffer prolonged intestinal paralysis or postoperative ileus (POI) leading to complications, such as infection and intestinal adhesions, which can extend hospitalization and increase readmission rates, and consequently increasing healthcare costs. Chinese medicine is effective for accelerating the recovery of gastrointestinal function after abdominal surgery. Xiangbin prescription (XBP) is the standard prescription for this purpose in our hospital; however, randomized controlled trials of it have not yet been conducted. This double-blind, randomized controlled clinical trial aims to recruit patients who have undergone abdominal surgery and experienced postoperative dysmotility to evaluate the efficacy and safety of XBP for preventing POI and accelerating recovery. The research will tackle the common problem of slow recovery of gastrointestinal function after surgery. The participants will be patients who undergo laparoscopic radical resection of rectal carcinoma or laparoscopic panhysterectomy of a benign lesion. Primary outcome measures will be time to first flatus, defecation, normal bowel sounds, and liquid/semi-liquid/general di...Continue Reading

References

Oct 11, 2008·Fundamental & Clinical Pharmacology·Luciana Gutterres AzevedoAna Luiza Muccillo-Baisch
Jan 9, 2009·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·M H MuellerM E Kreis
Feb 2, 2010·Journal of the American College of Surgeons·Theodor AsgeirssonAnthony J Senagore
Jan 9, 2013·Annals of Internal Medicine·An-Wen ChanDavid Moher
Jan 11, 2013·BMJ : British Medical Journal·An-Wen ChanDavid Moher
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Mar 11, 2015·Current Medical Research and Opinion·Filippo Sanfilippo, Gabriele Spoletini
Aug 24, 2016·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Si-Liang WenWei-Xuan Zhang
Sep 27, 2016·Journal of Visceral Surgery·A VenaraG Meurette
May 20, 2017·World Journal of Gastroenterology : WJG·Zhi JiangZhi-Qiang Chen

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Citations

Mar 2, 2021·World Journal of Gastroenterology : WJG·Qi-Cheng ChenZhi-Qiang Chen

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Methods Mentioned

BETA
hysterectomy

Software Mentioned

SPSS
Epidata
PEMS
Statistical Package for the Social Sciences ( SPSS )

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