XMAP215: a tip tracker that really moves

Cell
Charles L Asbury

Abstract

XMAP215 is a microtubule plus-end binding protein implicated in modulating microtubule dynamics. In this issue, Brouhard et al. (2008) propose a new mechanism to explain how XMAP215 promotes microtubule growth. They report that XMAP215 moves with the growing microtubule plus ends where it catalyzes the addition of tubulin subunits.

References

Jan 22, 2005·Current Opinion in Cell Biology·Anna Akhmanova, Casper C Hoogenraad
Mar 29, 2006·The Journal of Cell Biology·Jawdat Al-BassamAnthony Hyman
Jun 27, 2006·Nature·Jacob W J KerssemakersMarileen Dogterom
Sep 25, 2007·Molecular Cell·Kevin C Slep, Ronald D Vale
Dec 7, 2007·Nature·Peter BielingThomas Surrey
Jan 15, 2008·Cell·Gary J BrouhardAnthony A Hyman

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Citations

Mar 3, 2009·Photomedicine and Laser Surgery·James D Carroll
Jun 20, 2014·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Kamlesh K GuptaHolly V Goodson
Jul 19, 2012·Macromolecular Bioscience·Sílvia A FerreiraFrancisco M Gama

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