PMID: 6167408Jan 1, 1981Paper

XY pair associates with the synaptonemal complex of autosomal male-sterile translocations in pachytene spermatocytes of the mouse (Mus musculus)

Chromosoma
Jiri ForejtP Goetz

Abstract

Analysis of the chromosome behaviour at pachytene has been performed by means of the silver staining technique visualizing the synaptonemal complexes (SCs) in male mice heterozygous for the male-sterile translocations T(5;12)31Hm T(16;17)43H and T(7;19)145H, respectively. the T(9;17)138Ca male heterozygotes and T43H/T43H homozygous males were used as fertile controls. The sterile mice displayed a high frequency (about 60%) of pachytene spermatocytes with autosomal translocation configuration located in close vicinity of the XY pair. The dense round body (XAB), normally located near the X-chromosome axis in fertile males, exhibited abnormal affinity to translocation configuration in the sterile translocation heterozygotes. The incomplete synapsis of autosomes involved in translocation configuration was observed in more than 70% of the pachytene spermatocytes with the male-sterile translocations but less than 20% of the cells from T138Ca fertile male.s. A hypothesis relating the spermatogenic arrest of carriers of male-sterile rearrangements to the presumed interference with X chromosome inactivation in male meiosis is discussed.

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Citations

Jan 1, 1994·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·S C KingswoodI F Greenbaum
Sep 28, 2007·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Jirí Král
Sep 18, 2009·Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology·Marielle Cristina SchneiderDoralice Maria Cella
Feb 1, 1995·Theriogenology·S E GuiraaraesJ D Guimaraes
Oct 1, 1996·Trends in Genetics : TIG·J Forejt
Jan 19, 2013·Proceedings of the National Academy of Sciences of the United States of America·Tanmoy BhattacharyyaJiri Forejt
Aug 25, 2007·Genome Research·David HomolkaJiri Forejt
Jan 12, 1997·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·B Danielak-CzechE Slota
Feb 2, 2011·Cytogenetic and Genome Research·J KrálL Krkavcová
Oct 15, 1986·Experientia·A C Chandley
May 10, 2008·Cytogenetic and Genome Research·D A F Villagómez, A Pinton
Oct 8, 2011·International Journal of Andrology·R B SciuranoA J Solari
Jan 1, 1987·Differentiation; Research in Biological Diversity·C M NagamineG C Koo
Apr 20, 2016·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Shawn FayerAnna K Naumova
Sep 16, 2004·European Journal of Human Genetics : EJHG·Iben BacheNiels Tommerup
Oct 20, 2006·Human Reproduction·M DavissonM A Handel
Jul 10, 2021·Trends in Genetics : TIG·Jiri ForejtEmil Parvanov

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