PMID: 1066333Jan 1, 1976

Xylitol in relation to the incidence of dental caries

Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Beiheft
A Scheinin


Two clinical trials were carried out in order to evaluate differences in caries increment as influenced by various sugars. The first study involved almost complete substitution of sucrose (S) by fructose (F) or xylitol (X) during a period of 2 years. The second study comprised partial substitution, the effects of a S- or X-containing chewing gum being compared during 1 year. In the first trial there were no significant differences initially between the sugar groups; 35 subjects in the S-group, 38 in the F-group, and 52 in the X-group. During the entire study 10 subjects discontinued, in one case due to osmotic diarrhoea in the X-group, the other cases being due to difficulties in adhering to the strict diet, other personal reasons and in 3 cases due to excessive caries incidence. After 2 years the mean increment of decayed, missed and filled tooth surfaces was 7.2 in the S-group, 3.8 in the F-group and 0.0 in the X-group. The caries incidence was additionally expressed in combined quantitative and qualitative terms by considering also the changes in lesion size. Irrespective of the way of using these indices, a massive reduction of the caries increment was noted in the X-group as compared to the S-group. The second trial compri...Continue Reading

Related Concepts

Dietary Carbohydrates
Chewing gum (antigen)
Dental Caries
Gums Symptoms
Carious Dentin
Decayed, Missing, and Filled Teeth
Levulosa Ife
Deal Barratt Dillon Syndrome

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