Mar 14, 2013

Y-chromosome diversity in modern Bulgarians: new clues about their ancestry

PloS One
Sena KarachanakOrnella Semino

Abstract

To better define the structure and origin of the Bulgarian paternal gene pool, we have examined the Y-chromosome variation in 808 Bulgarian males. The analysis was performed by high-resolution genotyping of biallelic markers and by analyzing the STR variation within the most informative haplogroups. We found that the Y-chromosome gene pool in modern Bulgarians is primarily represented by Western Eurasian haplogroups with ∼ 40% belonging to haplogroups E-V13 and I-M423, and 20% to R-M17. Haplogroups common in the Middle East (J and G) and in South Western Asia (R-L23*) occur at frequencies of 19% and 5%, respectively. Haplogroups C, N and Q, distinctive for Altaic and Central Asian Turkic-speaking populations, occur at the negligible frequency of only 1.5%. Principal Component analyses group Bulgarians with European populations, apart from Central Asian Turkic-speaking groups and South Western Asia populations. Within the country, the genetic variation is structured in Western, Central and Eastern Bulgaria indicating that the Balkan Mountains have been permeable to human movements. The lineage analysis provided the following interesting results: (i) R-L23* is present in Eastern Bulgaria since the post glacial period; (ii) haplog...Continue Reading

  • References26
  • Citations12

References

  • References26
  • Citations12

Citations

Mentioned in this Paper

Short Tandem Repeat
Equine Laminitis
Y Chromosome
DNA, Mitochondrial
Indonesia Zebrafish
Chromosomes, Human, Y
Heraldry
Phylogeny
IDO1 gene
Human Geography

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