PMID: 9450541Feb 5, 1998Paper

Yeast gene YOR137c is involved in the activation of the yeast plasma membrane H+-ATPase by glucose

FEBS Letters
N de la FuenteF Portillo

Abstract

Glucose triggers transcriptional and post-transcriptional mechanisms that increase the level and activity of Saccharomyces cerevisiae plasma membrane H+-ATPase. We have studied the post-transcriptional activation of the enzyme by glucose and have found that the YOR137c gene product is implicated in this activation. Deletion of YOR137c does not affect the level of Pma1 at the plasma membrane, but disturbs the glucose-triggered Vmax increase of the enzyme. We propose that at least two independent mechanisms are involved in glucose activation of the H+-ATPase.

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Citations

Sep 5, 2002·Yeast·Anne G RosenwaldRichard A Kahn
Oct 20, 2010·Omics : a Journal of Integrative Biology·Nuno P MiraIsabel Sá-Correia
Feb 29, 2000·Biochimica Et Biophysica Acta·F Portillo
Apr 13, 2010·Fungal Genetics and Biology : FG & B·Anke GrünlerJürgen Wendland

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