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Yeast genetic interaction screens in the age of CRISPR/Cas

Current Genetics

Sep 27, 2018

Neil R AdamesJean Peccoud

Abstract

The ease of performing both forward and reverse genetics in Saccharomyces cerevisiae, along with its stable haploid state and short generation times, has made this budding yeast the consummate model eukaryote for genetics. The major advantage of using budding yeast for reverse genetics ...read more

Mentioned in this Paper

Biological Markers
Genome
CRISPR-Cas Systems
Saccharomyces cerevisiae allergenic extract
Gene Editing
Genetic Screening Method
Genetic Screening (Procedure)
Yeasts
Haploid Cell
Genomics
4
29
Paper Details
References
  • References1
  • Citations4
  • References1
  • Citations4
1

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Yeast genetic interaction screens in the age of CRISPR/Cas

Current Genetics

Sep 27, 2018

Neil R AdamesJean Peccoud

PMID: 30255296

DOI: 10.1007/s00294-018-0887-8

Abstract

The ease of performing both forward and reverse genetics in Saccharomyces cerevisiae, along with its stable haploid state and short generation times, has made this budding yeast the consummate model eukaryote for genetics. The major advantage of using budding yeast for reverse genetics ...read more

Mentioned in this Paper

Biological Markers
Genome
CRISPR-Cas Systems
Saccharomyces cerevisiae allergenic extract
Gene Editing
Genetic Screening Method
Genetic Screening (Procedure)
Yeasts
Haploid Cell
Genomics
4
29

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DNA Repair

DNA repair is critical to prevent detrimental mutations and maintain genomic stability that can otherwise lead to disease and disability. There are a number of different mechanisms of repair including base excision repair, direct repair, nucleotide excision repair and double-strand break repair. Discover the latest research on DNA repair here.

Yeast as a Model Organism (Yeast Model)

Yeast is a unicellular eukaryote that is utilized and manipulated in biological research to examine biological processes that underlie DNA replication, cell growth, and division, among numerous others. This feed focuses on yeast as a model organism.

Related Papers

Frontiers in Microbiology

CRISPR-UnLOCK: Multipurpose Cas9-Based Strategies for Conversion of Yeast Libraries and Strains

Frontiers in MicrobiologyOctober 6, 2017
Emily RoggenkampGregory C Finnigan
Paper Details
References
  • References1
  • Citations4
  • References1
  • Citations4
1
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