Yeast Infections after Esophagectomy: A Retrospective Analysis.

Scientific Reports
Marjolein HeukerMarleen van Oosten

Abstract

Esophageal malignancy is a disease with poor prognosis. Curative therapy incorporates surgery and is burdensome with high rates of infection morbidity and mortality. The role of yeast as causative organisms of post-esophagectomy infections is poorly defined. Consequently, the benefits of specific antifungal prophylactic therapy in improving patient outcome are unclear. Therefore, this study aimed at investigating the incidence of yeast infections at the University Medical Center Groningen among 565 post-esophagectomy patients between 1991 and 2017. The results show that 7.3% of the patients developed a yeast infection after esophageal resection with significantly increased incidence among patients suffering from diabetes mellitus. For patients with yeast infections, higher Acute Physiology and Chronic Health Evaluation (APACHE) II scores, more frequent intensive care unit readmissions, prolonged hospital stays and higher mortality rates were observed. One-year survival was significantly lower for patients with a yeast infection, as well as diabetes mellitus and yeast-positive pleural effusion. We conclude that the incidence of yeast infections following esophagectomy is considerable, and that patients with diabetes mellitus are...Continue Reading

References

Jun 15, 1999·Archives of Surgery·A P Borzotta, K Beardsley
Aug 14, 2001·American Journal of Respiratory and Critical Care Medicine·D C BergmansE E Stobberingh
Sep 29, 2001·British Journal of Anaesthesia·S TandonS V Baudouin
Jan 28, 2003·Diabetes Care·Baiju R Shah, Janet E Hux
Oct 15, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Olafur GudlaugssonDaniel Diekema
Oct 7, 2004·The Annals of Thoracic Surgery·B Zane AtkinsThomas A D'Amico
Jun 20, 2007·Mycoses·Ricard Jordà-MarcosUNKNOWN EPCAN Study Group
Jan 2, 2009·The New England Journal of Medicine·A M G A de SmetM J M Bonten
Mar 5, 2009·The Journal of Thoracic and Cardiovascular Surgery·Cameron D WrightUNKNOWN Society of Thoracic Surgeons General Thoracic Surgery Database
Jun 21, 2011·The Lancet Oncology·Katrin M SjoquistUNKNOWN Australasian Gastro-Intestinal Trials Group
Jul 1, 2011·Journal of Clinical Microbiology·Maiken Cavling ArendrupHelle Krogh Johansen
Jan 26, 2012·Current Opinion in Infectious Diseases·Anne Marie G A de SmetJan A J W Kluytmans
Feb 3, 2012·Critical Care Medicine·Elie AzoulayJean-François Timsit
Oct 10, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M C ArendrupUNKNOWN European Confederation of Medical Mycology
Mar 13, 2014·Therapeutics and Clinical Risk Management·Nur Yapar
Apr 22, 2015·The Journal of Surgical Research·Xiaoti LinXiaoming Xie
Oct 28, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Emily T MartinLinda Jaber
Apr 27, 2016·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J C Hurley
May 6, 2017·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·S-J LiL-Q Chen
Sep 6, 2017·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·N L PlantingaM J M Bonten

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surgical resection

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