Yessotoxin, a Promising Therapeutic Tool

Marine Drugs
Amparo AlfonsoLuis M Botana

Abstract

Yessotoxin (YTX) is a polyether compound produced by dinoflagellates and accumulated in filter feeding shellfish. No records about human intoxications induced by this compound have been published, however it is considered a toxin. Modifications in second messenger levels, protein levels, immune cells, cytoskeleton or activation of different cellular death types have been published as consequence of YTX exposure. This review summarizes the main intracellular pathways modulated by YTX and their pharmacological and therapeutic implications.

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Citations

Apr 15, 2017·Frontiers in Cell and Developmental Biology·Mónica Suárez Korsnes, Reinert Korsnes
May 31, 2018·Marine Drugs·Federica FarabegoliAna García Cabado
Jan 27, 2019·Scientific Reports·Jana AsselmanColin R Janssen
May 15, 2019·Marine Drugs·Bilal AhmadSangdun Choi
Apr 13, 2021·Environmental Science & Technology·Emmanuel Van AckerColin R Janssen
May 1, 2021·International Journal of Molecular Sciences·Assunta SaideChiara Lauritano
Jul 26, 2021·Harmful Algae·Teri L KingVera L Trainer

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Methods Mentioned

BETA
biosensor
transgenic

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