Yield of transesophageal echocardiography for nonbacterial thrombotic endocarditis and other cardiac sources of embolism in cancer patients with cerebral ischemia

The American Journal of Cardiology
Tanya DuttaJorge R Kizer

Abstract

Cerebrovascular events occur frequently in patients who succumb to cancer, and nonbacterial thrombotic endocarditis (NBTE) is a frequent postmortem finding in these patients. Despite the excellent diagnostic accuracy of transesophageal echocardiography (TEE) for cardiac sources of cerebral embolism, however, the prevalence of NBTE and other cardioembolic sources in patients with cancer and cerebral ischemia has not been investigated using this modality. This study examined the frequency of cardioembolic findings in consecutive patients with cancer referred to our institution for TEE evaluation of cerebrovascular events. The study cohort comprised 51 patients, of whom 18% had marantic vegetations, and 47% and 55% of whom had definite and definite or probable cardiac sources of embolism, respectively. The present study documents, for the first time, a high frequency of marantic endocarditis and other cardioembolic sources in patients with cancer and cerebrovascular events selected for TEE. This finding has important implications for evaluation and management in this patient population.

References

Jan 1, 1985·Medicine·F GrausJ B Posner
Dec 1, 1982·American Journal of Clinical Oncology·M M OkenP P Carbone
Oct 26, 1995·The New England Journal of Medicine·H G Bogren
May 22, 1998·Stroke; a Journal of Cerebral Circulation·M M SteinerR L Sacco
Dec 14, 2001·The New England Journal of Medicine·J L MasUNKNOWN Patent Foramen Ovale and Atrial Septal Aneurysm Study Group
Jan 7, 2003·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Harmony R ReynoldsItzhak Kronzon
Jun 9, 2004·Neurology·D M CestariL M DeAngelis
Aug 17, 2005·Circulation·Shunichi Homma, Ralph L Sacco

❮ Previous
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Citations

Dec 7, 2007·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·P Martín-MartorellJ I Cervera-Miguel
Sep 21, 2007·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Sanjay AsopaSunil K Ohri
Dec 17, 2009·Hematology·Brett L Cucchiara
Mar 8, 2011·Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics·Tomoyuki KonoMasayasu Matsumoto
Oct 15, 2013·Journal des maladies vasculaires·B VillemurG Pernod
Oct 1, 2013·Journal of Medical Ultrasonics·Yasuyuki HadanoMasunori Matsuzaki
Jan 15, 2016·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Muhamed SaricKirsten Tolstrup
Nov 26, 2009·Neurologic Clinics·Roger E Kelley
Jul 1, 2008·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Fabio Silvio TacconeSerge A Blecic
Jul 31, 2007·Gynecologic Oncology·Olivier MirJérôme Alexandre
Feb 14, 2013·Internal Medicine Journal·S F WongT John
Mar 4, 2014·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Akiko YamaneMichiyasu Suzuki
Apr 9, 2015·Journal of Neuro-oncology·Alexander E MerklerLisa M DeAngelis
Mar 18, 2008·Journal of the American College of Cardiology·Eleni DoufekiasJorge R Kizer
Jun 4, 2016·Journal of cardiology·Koki Nakanishi, Shunichi Homma
Jun 22, 2016·Wiener klinische Wochenschrift·Olivier WiggerStefan Bloechlinger
Oct 1, 2016·Echocardiography·Bhaskar BhardwajA Iain McGhie
Oct 11, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Naoki MatsumotoSen Yamagata
Jul 27, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nils D ArvoldStephanie E Weiss
Jul 13, 2014·Medicina clínica·Joan Gómez-JunyentMarta Terricabras Carol
Nov 30, 2010·Vascular Medicine·Saurabh SanonElie Mouhayar
Jul 6, 2014·Stroke; a Journal of Cerebral Circulation·Babak B NaviLisa M DeAngelis
Oct 31, 2014·Stroke; a Journal of Cerebral Circulation·James F MeschiaUNKNOWN Council on Hypertension
May 6, 2019·Journal of Neurointerventional Surgery·Alessandro SgrecciaUNKNOWN COMPO-Clot Investigators
Mar 5, 2015·Pediatric Emergency Care·Wendy L M Hunter
Jul 9, 2020·Journal of Stroke·Joonsang YooJi Hoe Heo
Oct 10, 2020·Brain Circulation·Deepak GoelUttam Shettigar
Mar 13, 2021·European Heart Journal Cardiovascular Imaging·Ariel CohenUNKNOWN chair of the 2018–2020 EACVI Scientific Documents Committee

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