YihQ is a sulfoquinovosidase that cleaves sulfoquinovosyl diacylglyceride sulfolipids

Nature Chemical Biology
Gaetano SpecialeEthan D Goddard-Borger

Abstract

Sulfoquinovose is produced by photosynthetic organisms at a rate of 10(10) tons per annum and is degraded by bacteria as a source of carbon and sulfur. We have identified Escherichia coli YihQ as the first dedicated sulfoquinovosidase and the gateway enzyme to sulfoglycolytic pathways. Structural and mutagenesis studies unveiled the sequence signatures for binding the distinguishing sulfonate residue and revealed that sulfoquinovoside degradation is widespread across the tree of life.

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Citations

Jan 5, 2018·Journal of the American Society for Mass Spectrometry·Nicholas A Williamson
Aug 3, 2017·Digestive Diseases and Sciences·Larry L BartonHenry C Lin
Dec 22, 2019·Marine Drugs·Gennaro Riccio, Chiara Lauritano
Dec 27, 2019·Journal of Phycology·María José IglesiasFernando López Ortiz
Sep 6, 2019·Nature Reviews. Microbiology·Mary Ann Moran, Bryndan P Durham
Feb 22, 2017·The Biochemical Journal·Ethan D Goddard-Borger, Spencer J Williams
May 24, 2020·Applied and Environmental Microbiology·Jinling LiSpencer J Williams
May 7, 2020·Marine Drugs·Gennaro RiccioChiara Lauritano
Mar 7, 2021·Vaccines·Akosiererem S SokariboAaron P White
Apr 2, 2021·ACS Central Science·Mahima SharmaSpencer J Williams
Oct 3, 2018·ACS Central Science·Palika AbayakoonSpencer J Williams
Feb 12, 2019·The Journal of Organic Chemistry·Palika AbayakoonSpencer J Williams
Nov 25, 2021·Chemical Society Reviews·Alexander J D SnowSpencer J Williams

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