Yoghurt accelerates the recovery of defence mechanisms against Streptococcus pneumoniae in protein-malnourished mice

The British Journal of Nutrition
Julio VillenaSusana Alvarez

Abstract

Experiments studied the effect of yoghurt on the recovery of defence mechanisms against Streptococcus pneumoniae respiratory infection in malnourished mice. Weaned mice were malnourished with a protein-free diet (PFD) for 21 d. Malnourished mice were made replete with a balanced diet (BD), yoghurt, or the BD with supplemental yoghurt (BD + Y) for 7, 14 or 21 d. The normal control (NC) group was fed the BD whereas malnourished control (MC) mice consumed only the PFD. Mice were challenged with pneumococci at the end of each dietary treatment. MC mice showed increased susceptibility to pneumococcal infection. Blood leucocytes, phagocyte activity and serum and bronco-alveolar anti-pneumococcal IgG and IgA were significantly lower in the MC than in the NC group. Repletion of malnourished mice with the BD for 21 d was necessary to obtain a response to infection similar to that of NC mice; however, administration of the BD + Y for 14 d was enough to normalise the immune defence mechanisms. Histological examination of MC lungs showed progressive loss of alveolar architecture. Lung injuries were significantly less pronounced in NC mice. Mice treated with the BD + Y for 14 d showed histological signs similar to the NC group. The present ...Continue Reading

References

Jan 1, 1990·Journal of Pediatric Gastroenterology and Nutrition·D GendrelM Chaussain
Feb 1, 1990·The American Review of Respiratory Disease·Y Sibille, H Y Reynolds
Jan 1, 1988·World Review of Nutrition and Dietetics·P Bourlioux, P Pochart
Jul 1, 1995·Journal of Dairy Science·G PerdigonN Gobbato
Mar 1, 1995·Journal of Dairy Science·E J SchiffrinA Donnet-Hughes
Sep 9, 1994·Science·R F Service
Aug 1, 1997·The American Journal of Clinical Nutrition·N S Scrimshaw, J P SanGiovanni
Jul 31, 1998·Nutrition·S Cunningham-Rundles, D H Lin
Oct 13, 1998·Alimentary Pharmacology & Therapeutics·S J Lewis, A R Freedman
Jan 14, 2000·The American Journal of Gastroenterology·J Saavedra
Mar 18, 2000·The Journal of Nutrition·K L Erickson, N E Hubbard
Mar 25, 2000·The American Journal of Clinical Nutrition·S N Meydani, W K Ha
Jul 29, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·S A MadhiK P Klugman
Sep 12, 2002·The Journal of Dairy Research·Paola Gauffin CanoGabriela Perdigón
Oct 31, 2002·American Journal of Respiratory and Critical Care Medicine·Sylvia KnappTom van der Poll
Jan 7, 2003·The Journal of Nutrition·Gerald T Keusch
Jul 19, 2003·Journal of Clinical Gastroenterology·Gregor ReidTodd R Klaenhammer
Dec 3, 2003·The Journal of Dairy Research·Paola Gauffin Cano, Gabriela Perdigón
Jul 28, 2004·The American Journal of Clinical Nutrition·Oskar AdolfssonRobert M Russell
Jun 3, 2005·The Journal of Nutrition·Julio VillenaSusana Alvarez
Jul 19, 2005·The British Journal of Nutrition·Francisco GuarnerLorenzo Morelli

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Citations

Sep 9, 2009·Journal of Medicinal Food·Cecilia HaroGraciela Agüero
Sep 6, 2008·Canadian Journal of Microbiology·Julio VillenaSusana Alvarez
Feb 18, 2011·Canadian Journal of Microbiology·Geeta Shukla, Ramandeep Kaur Sidhu
Aug 1, 2012·Microbiology and Immunology·Gabriela MarranzinoSusana Alvarez
Aug 21, 2014·Anais Da Academia Brasileira De Ciências·Jorge F de AzevedoEduardo J A Araújo
Jul 18, 2012·Anais Da Academia Brasileira De Ciências·Dirlene P LimaEduardo J A Araújo
Apr 12, 2017·Microorganisms·Julio Villena, Haruki Kitazawa
May 6, 2020·Critical Reviews in Food Science and Nutrition·Chengcheng RenPaul de Vos

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