Yoshinori Ohsumi's Nobel Prize for mechanisms of autophagy: from basic yeast biology to therapeutic potential

The Journal of the Royal College of Physicians of Edinburgh
D C Rubinsztein, R A Frake

Abstract

On 3 October 2016, Japanese cell biologist Yoshinori Ohsumi was awarded the Nobel Prize in Physiology or Medicine 'for his discoveries of mechanisms for autophagy'; autophagy being an intracellular degradation pathway that helps maintain cytoplasmic homeostasis. This commentary discusses Ohsumi's Nobel prize-winning work in context, before explaining the clinical relevance of autophagy.

Citations

Sep 25, 2020·Marine Drugs·Sergey A Dyshlovoy
Jan 18, 2020·Marine Drugs·Sergey A Dyshlovoy, Friedemann Honecker
Jun 15, 2020·Ageing Research Reviews·Xu LiLing Qin

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