Your brain on drugs: imaging of drug-related changes in the central nervous system

Radiographics : a Review Publication of the Radiological Society of North America, Inc
Benita Tamrazi, Jeevak Almast

Abstract

Drug abuse is a substantial problem in society today and is associated with significant morbidity and mortality. Various drugs are associated with serious complications affecting the brain, and it is critical to recognize the imaging findings of these complications to provide prompt medical management. The central nervous system (CNS) is a target organ for drugs of abuse as well as specific prescribed medications. Drugs of abuse affecting the CNS include cocaine, heroin, alcohol, amphetamines, toluene, and cannabis. Prescribed medications or medical therapies that can affect the CNS include immunosuppressants, antiepileptics, nitrous oxide, and total parenteral nutrition. The CNS complications of these drugs include neurovascular complications, encephalopathy, atrophy, infection, changes in the corpus callosum, and other miscellaneous changes. Imaging abnormalities indicative of these complications can be appreciated at both magnetic resonance (MR) imaging and computed tomography (CT). It is critical for radiologists to recognize complications related to drugs of abuse as well as iatrogenic effects of various medications. Therefore, diagnostic imaging modalities such as MR imaging and CT can play a pivotal role in the recogniti...Continue Reading

References

Jul 1, 1992·AJR. American Journal of Roentgenology·E BrownR G Ramsey
Oct 1, 1991·Stroke; a Journal of Cerebral Circulation·M DarasS Marks
Sep 13, 1990·The New England Journal of Medicine·S R LevineJ F Selwa
Oct 1, 1996·Neuroradiology·G QuaghebeurP J Milla
Apr 1, 1997·Surgical Neurology·R D FesslerF G Diaz
Feb 13, 1999·Neuroradiology·J Ruiz-MartínezJ F Martí Massó
Jan 3, 2001·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·J NeimanM Hillbom
Feb 20, 2003·AJR. American Journal of Roentgenology·Ciaran F KeoghDouglas A Graeb
Jun 18, 2003·Seizure : the Journal of the British Epilepsy Association·Felipe Antonio De MarcosFernano Cendes
Jul 24, 2003·Journal of Neurology, Neurosurgery, and Psychiatry·I M KiemeneijJ van Gijn
Jan 27, 2004·Journal of Neuroimmunology·Aftab Ahmed Ansari
Feb 21, 2004·International Journal of Cardiology·Michael B ErwinEfthymios N Deliargyris
Sep 17, 2004·Journal of Neurology·Alexander HeinrichAlexander V Khaw
Oct 27, 2005·The British Journal of Radiology·E Bartlett, D J Mikulis
Dec 13, 2005·Topics in Magnetic Resonance Imaging : TMRI·Rafael RojasJessica Borne
Dec 13, 2005·Topics in Magnetic Resonance Imaging : TMRI·Jessica BorneRafael Rojas
Aug 10, 2006·Spinal Cord·R M ShulmanM Tadros
Jan 31, 2007·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Kai Ming Chow, Cheuk Chun Szeto
Mar 3, 2007·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Kazuhiro HondaTatsuhiko Yuasa
Jul 11, 2007·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Ian G Hagan, Kashif Burney
Sep 11, 2007·Emergency Radiology·Lojana Tuntiyatorn, Jiraporn Laothamatas
Sep 27, 2007·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·S SenL E Braitman
Oct 20, 2007·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H InabaN C Daw
Jan 25, 2008·Obesity Surgery·Kamran QureshiGary A Abrams
Feb 15, 2008·AJNR. American Journal of Neuroradiology·W S BartynskiJ W Marsh
Oct 24, 2008·AJNR. American Journal of Neuroradiology·G ZuccoliN Pipitone
Nov 4, 2008·Nature Clinical Practice. Neurology·Sebastian Koch, Ralph L Sacco
Nov 11, 2008·Annals of the New York Academy of Sciences·Steven BermanEdythe D London
Dec 11, 2008·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Edith V Sullivan, Adolf Pfefferbaum
Jan 17, 2009·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Clive Harper
Aug 22, 2009·AJR. American Journal of Roentgenology·Pranshu SharmaJames N Scott
Oct 31, 2009·AJNR. American Journal of Neuroradiology·S GeibprasertT Krings
May 4, 2010·Mayo Clinic Proceedings·Jennifer E FugateAlejandro A Rabinstein
May 7, 2010·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Shahed ToossiS Andrew Josephson
Nov 3, 2010·The Breast : Official Journal of the European Society of Mastology·Hao LongTiehua Rong

❮ Previous
Next ❯

Citations

Oct 1, 2011·Topics in Magnetic Resonance Imaging : TMRI·Alexander FilatovGirish M Fatterpekar
May 8, 2013·Clinical Reviews in Allergy & Immunology·Jonathan B FordTimothy E Albertson
Jul 16, 2014·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Ahmed Abdel Khalek Abdel RazekMauricio Castillo
Mar 4, 2014·Radiologic Clinics of North America·Michael RyanHemant A Parmar
Dec 18, 2013·Seminars in Roentgenology·Daniel J Boulter, Pamela W Schaefer
May 30, 2015·Journal of Neurosurgery·Chun-Hung TsengFung-Chang Sung
Jul 15, 2015·Clinical Neurology and Neurosurgery·Yuan WuXing Wei
Oct 25, 2016·Radiología·A Montoya-Filardi, M Mazón
Feb 6, 2018·The Neuroradiology Journal·Shuo LiMark Rosovsky
Mar 29, 2019·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Pradeep GoyalRajiv Mangla
Dec 18, 2013·Pharmacological Reviews·Suzanne WoodStephan G Anagnostaras
Jan 11, 2018·Radiographics : a Review Publication of the Radiological Society of North America, Inc·David D B BatesMariza O Clement
Jun 22, 2019·Central Nervous System Agents in Medicinal Chemistry·Saganuwan Alhaji Saganuwan
Nov 14, 2019·Korean Journal of Neurotrauma·Alexandrina S NikovaTheodossios Birbilis
Oct 8, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jennifer L McCartyWaleed Brinjikji
Oct 8, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Arthur M de OliveiraLeandro T Lucato
Aug 2, 2018·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Marinos Kontzialis, Thierry A G M Huisman
Jul 10, 2019·British Journal of Hospital Medicine·Tharunniya VamadevanMaria Filyridou
Nov 23, 2016·Journal of Endocrinological Investigation·C SavopoulosA I Hatzitolios
Jul 11, 2018·JAMA Neurology·Vilakshan AlambyanCiro Ramos-Estebanez
Dec 27, 2019·Journal of Pediatric Hematology/oncology·Sarah DabaghDeepa Bhojwani
Aug 5, 2020·Revue neurologique·A L AlunguleseJ Prieto Montalvo
Jun 23, 2020·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Kapil Zirpe, Shrirang N Bamne
Jun 23, 2020·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Ankush SinglaMinnu M Panditrao
Apr 23, 2021·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Nicholas S PhillipsNicole J Ullrich
Apr 28, 2021·Magnetic Resonance Imaging Clinics of North America·Steven P Meyers
Nov 11, 2021·Drug Research·Sulaiman Mohammed Alnasser

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

AJNR. American Journal of Neuroradiology
S GeibprasertT Krings
AJR. American Journal of Roentgenology
Giulio Zuccoli, Nicolò Pipitone
© 2021 Meta ULC. All rights reserved