(Z)-2-(5-Fluoro-2-oxoindolin-3-yl-idene)-N-phenyl-hydrazinecarbothio-amide.

Acta Crystallographica. Section E, Structure Reports Online
Amna Qasem AliHoong-Kun Fun

Abstract

The title compound, C(15)H(11)FN(4)OS, crystallizes with three independent mol-ecules (A, B and C) in the asymmetric unit. The dihedral angles between the nine-membered 5-fluoro-indolin-2-one ring system and the benzene ring are 22.14 (11), 12.56 (11) and 3.70 (11)° in mol-ecules A, B and C, respectively. In all three mol-ecules, intra-molecular cyclic N-H⋯O and C-H⋯S hydrogen-bonding inter-actions [graph set S(6)] are present in the N-N-C-N chain between the ring systems. In the crystal, the A mol-ecules form centrosymmetric cyclic dimers through inter-molecular N-H⋯O hydrogen bonds, which are linked into a supramolecular chain along [100] via C-H⋯F interactions; each type of hydrogen bond has graph set graph set R(2) (2)(8). A similar chain stabilised by similar interactions and also along [100] but, comprising alternating molecules of B and C is found. The latter chains are connected via C-H⋯S interactions, forming a layer with a zigzag topology parallel to (001).

References

Jul 20, 2002·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Seshaiah Krishnan SridharAtmakuru Ramesh
Dec 25, 2007·Acta Crystallographica. Section A, Foundations of Crystallography·George M Sheldrick
Jan 28, 2009·Acta Crystallographica. Section D, Biological Crystallography·Anthony L Spek
May 16, 2009·Anti-cancer Agents in Medicinal Chemistry·K L VineD Skropeta
Jan 1, 2010·Acta Crystallographica. Section E, Structure Reports Online·Humayun PervezMohammad S Iqbal
Jan 1, 2010·Acta Crystallographica. Section E, Structure Reports Online·Muhammad RamzanM Nawaz Tahir
Dec 27, 2011·Acta Crystallographica. Section E, Structure Reports Online·Amna Qasem AliHoong-Kun Fun
Dec 27, 2011·Acta Crystallographica. Section E, Structure Reports Online·Amna Qasem AliHoong-Kun Fun

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Citations

May 17, 2012·Acta Crystallographica. Section E, Structure Reports Online·Amna Qasem AliHoong-Kun Fun
May 17, 2012·Acta Crystallographica. Section E, Structure Reports Online·Amna Qasem AliHoong-Kun Fun
May 17, 2012·Acta Crystallographica. Section E, Structure Reports Online·Amna Qasem AliHoong-Kun Fun
May 19, 2012·Acta Crystallographica. Section E, Structure Reports Online·Amna Qasem AliHoong-Kun Fun
Jun 20, 2015·Acta Crystallographica. Section E, Crystallographic Communications·Viviane C D BittencourtAdriano Bof de Oliveira
Nov 6, 2012·Acta Crystallographica. Section E, Structure Reports Online·Amna Qasem AliHoong-Kun Fun

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