Zaleplon (Sonata) oral sedation for outpatient third molar extraction surgery

Anesthesia Progress
Steven I GanzbergF Michael Beck


Zalpelon was compared with triazolam for oral sedation in a third molar surgery model using a double-blind crossover design. Factors such as anxiolysis, amnesia, and quality of sedation were assessed. Of the 14 participants who completed the study, zaleplon sedation was found to be similar to triazolam sedation in all regards except that recovery from zaleplon was more rapid.


Jan 1, 1989·Pharmacology & Toxicology·J S Schou
Aug 1, 1995·Journal of Clinical Psychopharmacology·P D KrobothR B Smith
Feb 1, 1993·Oral Surgery, Oral Medicine, and Oral Pathology·E KaufmanR A Dionne
Aug 1, 1997·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·C W BertholdS E Corey
Apr 22, 1999·Biopharmaceutics & Drug Disposition·A S RosenS M Troy


Sep 29, 2007·Anesthesia Progress·Mark DonaldsonBrian Chanpong
Nov 21, 2012·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Paul G SimsDavid W Todd
Sep 14, 2010·Dental Clinics of North America·Chester J SokolowskiSean G Boynes

Related Concepts

Surgery, Day
Anesthesia Recovery Period
Anesthesia, Dental
Double-Blind Method
Structure of Wisdom Tooth

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